Context.—Histiocytic sarcoma is a rare neoplasm of mature histiocytes with an aggressive
clinical course that can arise de novo or from a low-grade B-cell lymphoma. In particular …

Disease progression in myelodysplastic syndromes (MDS), myelodysplastic-
myeloproliferative neoplasms (MDS/MPN), and myeloproliferative neoplasms (MPN) …

Recent studies have demonstrated recurrent activating mutations involving the classical
MAPK and PI3K signaling pathways in a large proportion of histiocytic neoplasms, such as …

Histiocytic sarcoma is a rare malignant neoplasm that may occur de novo or in the context of
a previous hematologic malignancy or mediastinal germ cell tumor. Here, we performed …

Tumors derived from histiocytic and dendritic cells encompass a large and heterogeneous
group of neoplastic and reactive conditions, and their diagnosis is challenging both for …

The bone marrow is a preferential site for both reactive and neoplastic histiocytic
proliferations. The differential diagnosis ranges from reactive histiocyte hyperplasia in …

Histiocytic sarcoma (HS) is a rare and aggressive tumor in humans with no universally
agreed standard of care therapy. Spontaneous canine HS exhibits increased prevalence in …

Histiocytic sarcoma (HS) is an aggressive malignant neoplasm of dendritic cell origin that is
common in certain breeds of dogs. High prevalence of fatal, disseminated HS has been …

Histiocytic sarcoma (HS) is a rare hematological malignancy, which exhibits morphological
and immunophenotypic features of histiocytes. A standard therapy for HS has not yet been …

Abstract The 2008 World Health Organization (WHO) diagnostic criteria of histiocytic and
dendritic cell neoplasms from hematopoietic and lymphoid tissues no longer required the …