Harmonized cross-species cell atlases of trigeminal and dorsal root ganglia

SA Bhuiyan, M Xu, L Yang, E Semizoglou, P Bhatia… - Science …, 2024 - science.org
Sensory neurons in the dorsal root ganglion (DRG) and trigeminal ganglion (TG) are
specialized to detect and transduce diverse environmental stimuli to the central nervous …

Satellite Glial Cells: No Longer the Most Overlooked Glia

SJ Birren, LV Goodrich… - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
Many glial biologists consider glia the neglected cells of the nervous system. Among all the
glia of the central and peripheral nervous system, satellite glia may be the most often …

Satellite glial cells bridge sensory neuron crosstalk in visceral pain and cross-organ sensitization

LY Qiao - Journal of Pharmacology and Experimental …, 2024 - jpet.aspetjournals.org
Following colonic inflammation, the uninjured bladder afferent neurons are also activated.
The mechanisms and pathways underlying this sensory neuron cross-activation (from …

[HTML][HTML] Transcriptional profiles of non-neuronal and immune cells in mouse trigeminal ganglia

J Mecklenburg, SA Shein, M Malmir… - Frontiers in Pain …, 2023 - frontiersin.org
Non-neuronal cells constitute 90%–95% of sensory ganglia. These cells, especially glial
and immune cells, play critical roles in the modulation of sensory neurons. This study aimed …

[HTML][HTML] Characterisation of GFAP-expressing glial cells in the dorsal root ganglion after spared nerve injury

EA Konnova, AF Deftu, P Chu Sin Chung… - International Journal of …, 2023 - mdpi.com
Satellite glial cells (SGCs), enveloping primary sensory neurons' somas in the dorsal root
ganglion (DRG), contribute to neuropathic pain upon nerve injury. Glial fibrillary acidic …

Satellite glial cell manipulation prior to axotomy enhances developing dorsal root ganglion central branch regrowth into the spinal cord

RI Brown, HM Barber, S Kucenas - Glia, 2024 - Wiley Online Library
The central and peripheral nervous systems (CNS and PNS, respectively) exhibit
remarkable diversity in the capacity to regenerate following neuronal injury with PNS injuries …

[HTML][HTML] Expression of Cannabinoid Receptors in the Trigeminal Ganglion of the Horse

R Zamith Cunha, A Semprini, G Salamanca… - International Journal of …, 2023 - mdpi.com
Cannabinoid receptors are expressed in human and animal trigeminal sensory neurons;
however, the expression in the equine trigeminal ganglion is unknown. Ten trigeminal …

[HTML][HTML] Dissociation and Culture of Adult Mouse Satellite Glial Cells

R Tonello, S Davidson, T Berta - Bio-protocol, 2023 - ncbi.nlm.nih.gov
Satellite glial cells (SGCs) are a type of glial cell population that originates from neural crest
cells. They ultimately migrate to surround the cell bodies of neurons in the ganglia of the …

Satellite glial contact enhances differentiation and maturation of human iPSC-derived sensory neurons

CJ LeBlang, MF Pazyra-Murphy, ES Silagi, S Dasgupta… - bioRxiv, 2024 - biorxiv.org
Sensory neurons generated from induced pluripotent stem cells (iSNs) are used to model
human peripheral neuropathies, however current differentiation protocols produce sensory …

[HTML][HTML] Single-nucleus transcriptome analysis reveals transcriptional profiles of circadian clock and pain related genes in human and mouse trigeminal ganglion

Y Chu, Y Wu, S Jia, K Xu, J Liu, L Mai, W Fan… - Frontiers in …, 2023 - frontiersin.org
Introduction Clinical studies have revealed the existence of circadian rhythms in pain
intensity and treatment response for chronic pain, including orofacial pain. The circadian …