To adapt to and anticipate rhythmic changes in the environment such as daily light–dark and
temperature cycles, internal timekeeping mechanisms called biological clocks evolved in a …

The relatively simple Drosophila circadian clock circuit consists of 150 clock neurons that
coordinate rhythmic behavior and physiology, which are generally classified based on …

The circadian clock orchestrates daily changes in physiology and behavior to ensure
internal temporal order and optimal timing across the day. In animals, a central brain clock …

Drosophila's dorsal clock neurons (DNs) consist of four clusters (DN1as, DN1ps, DN2s, and
DN3s) that largely differ in size. While the DN1as and the DN2s encompass only two …

The circadian clock regulates animal physiological activities. How temperature reorganizes
circadian-dependent physiological activities remains elusive. Here, using in-vivo two-photon …

In adulthood, sleep-wake rhythms are one of the most prominent behaviors under circadian
control. However, during early life, sleep is spread across the 24-hour day. The mechanism …

In metazoan organisms, circadian (∼ 24 h) rhythms are regulated by pacemaker neurons
organized in a master–slave hierarchy. Although it is widely accepted that master …

The sleep–wake cycle is determined by circadian and sleep homeostatic processes.
However, the molecular impact of these processes and their interaction in different brain cell …

Human generated environmental change profoundly affects organisms that reside across
diverse ecosystems. Although nervous systems evolved to flexibly sense, respond, and …

Sex peptide (SP), a seminal fluid protein of Drosophila melanogaster males, has been
described as driving a virgin-to-mated switch in females, through eliciting an array of …