Alzheimer disease (AD) is associated with multiple etiologies and pathological mechanisms,
among which oxidative stress (OS) appears as a major determinant. Intriguingly, OS arises …

Abstract Neurodegenerative diseases (NDs), including Alzheimer's disease (AD),
Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), exhibit high phenotypic …

An unresolved question for the understanding of Alzheimer's disease (AD) pathophysiology
is why a significant percentage of amyloid-β (Aβ)-positive cognitively unimpaired (CU) …

Timely and accurate diagnosis of Alzheimer's disease (AD) in clinical practice remains
challenging. PET and CSF biomarkers are the most widely used biomarkers to aid diagnosis …

Recently, low-sensitive plasma assays have been replaced by new ultra-sensitive assays
such as single molecule enzyme-linked immunosorbent assay (Simoa), the Mesoscale …

Introduction Plasma biomarkers—cost effective, non‐invasive indicators of Alzheimer's
disease (AD) and related disorders (ADRD)—have largely been studied in clinical research …

By definition, aging is a natural, gradual and continuous process. On the other hand, frailty
reflects the increase in vulnerability to stressors and shortens the time without disease …

Background Data from human studies suggest that immune dysregulation is associated with
Alzheimer's disease (AD) pathology and cognitive decline and that neurites may be affected …

The health inequities facing women and gender diverse people are well known. 1 Sex
differences exist in both prevalence and manifestation of numerous disorders, 1 making it …

Importance Plasma biomarkers show promise for identifying Alzheimer disease (AD)
neuropathology and neurodegeneration, but additional examination among diverse …