[HTML][HTML] Stimuli-responsive nanocarriers for drug delivery, tumor imaging, therapy and theranostics
P Mi - Theranostics, 2020 - ncbi.nlm.nih.gov
In recent years, much progress has been motivated in stimuli-responsive nanocarriers,
which could response to the intrinsic physicochemical and pathological factors in diseased …
which could response to the intrinsic physicochemical and pathological factors in diseased …
[HTML][HTML] Polymersome-based protein drug delivery–quo vadis?
MG Gouveia, JP Wesseler, J Ramaekers… - Chemical Society …, 2023 - pubs.rsc.org
Protein-based therapeutics are an attractive alternative to established therapeutic
approaches and represent one of the fastest growing families of drugs. While many of these …
approaches and represent one of the fastest growing families of drugs. While many of these …
Block copolymer solution self‐assembly: Recent advances, emerging trends, and applications
M Karayianni, S Pispas - Journal of Polymer Science, 2021 - Wiley Online Library
The self‐assembly process of block copolymers (BCPs) in solution has been at the focus of
extended scientific research over the past several decades owing to the astonishing …
extended scientific research over the past several decades owing to the astonishing …
[HTML][HTML] Anti-PEG antibodies compromise the integrity of PEGylated lipid-based nanoparticles via complement
ME Senti, CA de Jongh, K Dijkxhoorn… - Journal of Controlled …, 2022 - Elsevier
PEGylation of lipid-based nanoparticles and other nanocarriers is widely used to increase
their stability and plasma half-life. However, either pre-existing or de novo formed anti-PEG …
their stability and plasma half-life. However, either pre-existing or de novo formed anti-PEG …
Nanodiscs: a versatile nanocarrier platform for cancer diagnosis and treatment
J Bariwal, H Ma, GA Altenberg, H Liang - Chemical Society Reviews, 2022 - pubs.rsc.org
Cancer therapy is a significant challenge due to insufficient drug delivery to the cancer cells
and non-selective killing of healthy cells by most chemotherapy agents. Nano-formulations …
and non-selective killing of healthy cells by most chemotherapy agents. Nano-formulations …
Actively targeted nanomedicines for precision cancer therapy: Concept, construction, challenges and clinical translation
The development of targeted nanomedicines for cancer therapy has been an utmost focus of
research across different fields including materials science, nanotechnology, biotechnology …
research across different fields including materials science, nanotechnology, biotechnology …
Stimuli-responsive polymersomes for biomedical applications
Polymersomes, the structural analogues of liposomes, are hollow structures enclosed by a
bilayer membrane made from amphiphilic copolymers. Polymersomes have been proposed …
bilayer membrane made from amphiphilic copolymers. Polymersomes have been proposed …
Biodegradable polymeric nanoparticles for therapeutic cancer treatments
Polymeric nanoparticles have tremendous potential to improve the efficacy of therapeutic
cancer treatments by facilitating targeted delivery to a desired site. The physical and …
cancer treatments by facilitating targeted delivery to a desired site. The physical and …
1, 2-Dithiolane-derived dynamic, covalent materials: cooperative self-assembly and reversible cross-linking
X Zhang, RM Waymouth - Journal of the American Chemical …, 2017 - ACS Publications
The use of dithiolane-containing polymers to construct responsive and dynamic networks is
an attractive strategy in material design. Here, we provide a detailed mechanistic study on …
an attractive strategy in material design. Here, we provide a detailed mechanistic study on …
Chemical approaches to synthetic drug delivery systems for systemic applications
D Braatz, M Cherri, M Tully, M Dimde… - Angewandte Chemie …, 2022 - Wiley Online Library
Poor water solubility and low bioavailability of active pharmaceutical ingredients (APIs) are
major causes of friction in the pharmaceutical industry and represent a formidable hurdle for …
major causes of friction in the pharmaceutical industry and represent a formidable hurdle for …