Over the past decade, the landscape of molecular synthesis has gained major impetus by
the introduction of late-stage functionalization (LSF) methodologies. C–H functionalization …

Industrialization and other human activity represent significant environmental hazards. Toxic
contaminants can harm a comprehensive platform of living organisms in their particular …

Biocatalysis, using defined enzymes for organic transformations, has become a common
tool in organic synthesis, which is also frequently applied in industry. The generally high …

The applications of fluorine in drug design continue to expand, facilitated by an improved
understanding of its effects on physicochemical properties and the development of synthetic …

Molecular oxygen as a green, non-toxic and inexpensive oxidant has displayed lots of
advantages compared with other oxidants towards more selective, sustainable, and …

Advances in technology have allowed for the sensitive, specific, and simultaneous
quantitative profiling of steroid precursors, bioactive steroids and inactive metabolites …

Enzymes are complex biological catalysts and are critical to life. Most oxidations of
chemicals are catalyzed by cytochrome P450 (P450, CYP) enzymes, which generally utilize …

The demand to develop and produce eco-friendly alternatives for food packaging is
increasing. The huge negative impact that the disposal of so-called “single-use plastics” has …

Microplastics (MPs) are ubiquitous pollutants persisting almost everywhere in the
environment. With the increase in anthropogenic activities, MP accumulation is increasing …

Direct C–H bond functionalization catalyzed by non-precious transition metals is an
attractive strategy in synthetic chemistry. Compared with the precious metals rhodium …