Drug discovery targeting nuclear receptor binding SET domain protein 2 (NSD2)
Nuclear receptor binding SET domain proteins (NSDs) catalyze the mono-or dimethylation
of histone 3 lysine 36 (H3K36me1 and H3K36me2), using S-adenosyl-l-methionine (SAM) …
of histone 3 lysine 36 (H3K36me1 and H3K36me2), using S-adenosyl-l-methionine (SAM) …
Mixed phenotype acute leukemia: current approaches to diagnosis and treatment
TB Alexander, E Orgel - Current Oncology Reports, 2021 - Springer
Abstract Purpose of Review Mixed phenotype acute leukemia (MPAL) is a rare subtype of
acute leukemia with features of both acute lymphoblastic leukemia (ALL) and acute myeloid …
acute leukemia with features of both acute lymphoblastic leukemia (ALL) and acute myeloid …
[HTML][HTML] Deep learning detects acute myeloid leukemia and predicts NPM1 mutation status from bone marrow smears
The evaluation of bone marrow morphology by experienced hematopathologists is essential
in the diagnosis of acute myeloid leukemia (AML); however, it suffers from a lack of …
in the diagnosis of acute myeloid leukemia (AML); however, it suffers from a lack of …
[HTML][HTML] Acute myeloid leukemia
A Vakiti, P Mewawalla - 2018 - europepmc.org
Objectives: Identify the epidemiology of acute myeloid leukemia. Describe the physical exam
of a patient with acute myeloid leukemia, Review the management of acute myeloid …
of a patient with acute myeloid leukemia, Review the management of acute myeloid …
[HTML][HTML] Significance of NPM1 gene mutations in AML
A Hindley, MA Catherwood, MF McMullin… - International journal of …, 2021 - mdpi.com
The aim of this literature review is to examine the significance of the nucleophosmin 1
(NPM1) gene in acute myeloid leukaemia (AML). This will include analysis of the structure …
(NPM1) gene in acute myeloid leukaemia (AML). This will include analysis of the structure …
[HTML][HTML] Measurable residual disease in acute myeloid leukemia using flow cytometry: a review of where we are and where we are going
C Dix, TH Lo, G Clark, E Abadir - Journal of clinical medicine, 2020 - mdpi.com
The detection of measurable residual disease (MRD) has become a key investigation that
plays a role in the prognostication and management of several hematologic malignancies …
plays a role in the prognostication and management of several hematologic malignancies …
Advances in AI‐based cancer cytopathology
Y Yang, S Guan, Z Ou, W Li, L Yan… - Interdisciplinary …, 2023 - Wiley Online Library
Cytopathological examination plays a crucial role in cancer diagnosis as it reflects the
cellular pathology of cancer. However, this process traditionally relies on the visual …
cellular pathology of cancer. However, this process traditionally relies on the visual …
[HTML][HTML] Targeting neutrophil extracellular traps: A novel strategy in hematologic malignancies
R Liu, J Zhang, FR Lima, J Zeng, Q Nian - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Neutrophil extracellular traps (NETs) have emerged as a critical factor in malignant
hematologic disease pathogenesis. These structures, comprising DNA, histones, and …
hematologic disease pathogenesis. These structures, comprising DNA, histones, and …
[HTML][HTML] Unsupervised flow cytometry analysis allows for an accurate identification of minimal residual disease assessment in acute myeloid leukemia
Simple Summary In acute myeloid leukemia (AML), minimal/measurable residual disease
(MRD) can be assessed based on molecular markers or immunophenotypic features …
(MRD) can be assessed based on molecular markers or immunophenotypic features …
The potential role and mechanism of circRNAs in Ferroptosis: A comprehensive review
J Arabpour, K Rezaei, JY Khojini, S Razi… - … -Research and Practice, 2024 - Elsevier
Cell death encompasses various mechanisms, including necrosis and apoptosis.
Ferroptosis, a unique form of regulated cell death, emerged as a non-apoptotic process …
Ferroptosis, a unique form of regulated cell death, emerged as a non-apoptotic process …