[HTML][HTML] Exosomes as mediators of intercellular crosstalk in metabolism

R Isaac, FCG Reis, W Ying, JM Olefsky - Cell metabolism, 2021 - Elsevier
Exosomes are nanoparticles secreted by all cell types and are a large component of the
broader class of nanoparticles termed extracellular vesicles (EVs). Once secreted …

[HTML][HTML] The biology, function, and applications of exosomes in cancer

J Liu, L Ren, S Li, W Li, X Zheng, Y Yang, W Fu… - … Pharmaceutica Sinica B, 2021 - Elsevier
Exosomes are cell-derived nanovesicles with diameters from 30 to 150 nm, released upon
fusion of multivesicular bodies with the cell surface. They can transport nucleic acids …

Engineered extracellular vesicles and their mimetics for cancer immunotherapy

C Liu, Y Wang, L Li, D He, J Chi, Q Li, Y Wu… - Journal of Controlled …, 2022 - Elsevier
Extracellular vesicles (EVs) are heterogeneous membranous vesicles secreted by living
cells that are involved in many physiological and pathological processes as intermediaries …

Zeta potential of extracellular vesicles: Toward understanding the attributes that determine colloidal stability

G Midekessa, K Godakumara, J Ord, J Viil… - ACS …, 2020 - ACS Publications
Extracellular vesicles (EVs), including exosomes and microvesicles (< 200 nm), play a vital
role in intercellular communication and carry a net negative surface charge under …

[HTML][HTML] Primary prostate cancer educates bone stroma through exosomal pyruvate kinase M2 to promote bone metastasis

J Dai, J Escara-Wilke, JM Keller, Y Jung… - Journal of Experimental …, 2019 - rupress.org
Prostate cancer (PCa) metastasizes selectively to bone through unknown mechanisms. In
the current study, we identified exosome-mediated transfer of pyruvate kinase M2 (PKM2) …

Exosome treatment enhances anti-inflammatory M2 macrophages and reduces inflammation-induced pyroptosis in doxorubicin-induced cardiomyopathy

DK Singla, TA Johnson, Z Tavakoli Dargani - Cells, 2019 - mdpi.com
Doxorubicin (Dox) is an effective antineoplastic agent used to treat cancers, but its use is
limited as Dox induces adverse cardiotoxic effects. Dox-induced cardiotoxicity (DIC) can …

[HTML][HTML] Exosomes and extracellular vesicles: Rethinking the essential values in cancer biology

A Yokoi, T Ochiya - Seminars in Cancer Biology, 2021 - Elsevier
Extracellular vesicles (EVs) such as exosomes are released by all living cells and contain
diverse bioactive molecules, including nucleic acids, proteins, lipids, and metabolites …

[HTML][HTML] Extracellular vesicles in ovarian cancer chemoresistance, metastasis, and immune evasion

W Tian, N Lei, J Zhou, M Chen, R Guo, B Qin, Y Li… - Cell Death & …, 2022 - nature.com
Chemoresistance and metastasis are the major challenges for the current ovarian cancer
treatment. Understanding the mechanisms of ovarian cancer progression and metastasis is …

Extracellular vesicles as biomarkers in cancer immunotherapy

M Mathew, M Zade, N Mezghani, R Patel, Y Wang… - Cancers, 2020 - mdpi.com
Simple Summary Extracellular vesicles (EVs) are small particles found throughout the body.
EVs are released by living cells and contain cargo representing the cell of origin. In recent …

DC-based vaccines for cancer immunotherapy

C Fu, L Zhou, QS Mi, A Jiang - Vaccines, 2020 - mdpi.com
As the sentinels of the immune system, dendritic cells (DCs) play a critical role in initiating
and regulating antigen-specific immune responses. Cross-priming, a process that DCs …