Chronic inflammatory airway diseases, including asthma, chronic rhinosinusitis, eosinophilic
COPD and allergic rhinitis are a global health concern. Despite the coexistence of these …

Chronic rhinosinusitis (CRS) is a troublesome, chronic inflammatory disease that affects
over 10% of the adult population, causing decreased quality of life, lost productivity, and lost …

Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) characterized by a type 2
immune signature often have severe and recurrent disease. Lower airway conditions such …

Chronic rhinosinusitis with nasal polyps (CRSwNP) is generally associated with eosinophilic
tissue infiltration linked to type 2 inflammation and characterized by elevated levels of …

Group 2 innate lymphoid cells (ILC2s) secrete type 2 cytokines, which protect against
parasites but can also contribute to a variety of inflammatory airway diseases. We report …

Chronic rhinosinusitis (CRS) affects up to 12% of the general population and is traditionally
divided into two main phenotypic subsets, based on the presence of nasal polyps …

Asthma is a complex respiratory disease that varies in severity and response to treatment.
Several asthma phenotypes with unique clinical and inflammatory characteristics have been …

Chronic rhinosinusitis (CRS) often is characterized by an eosinophilic inflammatory pattern,
nowadays referred to as type 2 inflammation, although the mucosal inflammation is …

Rationale: The mechanisms that underlie the pathogenesis of chronic rhinosinusitis without
nasal polyps (CRSsNP), chronic rhinosinusitis with nasal polyps (CRSwNP), and aspirin …

Chronic rhinosinusitis (CRS) is a broad clinical syndrome that is characterized by prolonged
mucosal inflammation of the nose and paranasal sinuses, and is typically divided into two …