A brief insight into the etiology, genetics, and immunology of polycystic ovarian syndrome (PCOS)

S Siddiqui, S Mateen, R Ahmad, S Moin - Journal of assisted reproduction …, 2022 - Springer
Polycystic ovarian syndrome (PCOS) is a prevailing endocrine and metabolic disorder
occurring in about 6–20% of females in reproductive age. Most symptoms of PCOS arise …

Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications

E Diamanti-Kandarakis, A Dunaif - Endocrine reviews, 2012 - academic.oup.com
Polycystic ovary syndrome (PCOS) is now recognized as an important metabolic as well as
reproductive disorder conferring substantially increased risk for type 2 diabetes. Affected …

Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome

Y Shi, H Zhao, Y Shi, Y Cao, D Yang, Z Li, B Zhang… - Nature …, 2012 - nature.com
Following a previous genome-wide association study (GWAS 1) including 744 cases and
895 controls, we analyzed genome-wide association data from a new cohort of Han Chinese …

[HTML][HTML] The role of polymorphism in various potential genes on polycystic ovary syndrome susceptibility and pathogenesis

H Chaudhary, J Patel, NK Jain, R Joshi - Journal of ovarian research, 2021 - Springer
Polycystic ovary syndrome (PCOS) is the most common endocrinopathies affecting the early
reproductive age in women, whose pathophysiology perplexes many researchers till today …

The molecular-genetic basis of functional hyperandrogenism and the polycystic ovary syndrome

HF Escobar-Morreale, M Luque-Ramírez… - Endocrine …, 2005 - academic.oup.com
The genetic mechanisms underlying functional hyperandrogenism and the polycystic ovary
syndrome (PCOS) remain largely unknown. Given the large number of genetic variants …

Genetics of the polycystic ovary syndrome

G Kosova, M Urbanek - Molecular and cellular endocrinology, 2013 - Elsevier
Polycystic ovary syndrome (PCOS) is a highly complex endocrine disorder, characterized by
hyperandrogenemia, menstrual irregularities and polycystic ovaries. A strong genetic …

Systematic review: association of polycystic ovary syndrome with metabolic syndrome and non‐alcoholic fatty liver disease

A Baranova, TP Tran, A Birerdinc… - Alimentary …, 2011 - Wiley Online Library
Aliment Pharmacol Ther 2011; 33: 801–814 Summary Background Polycystic ovary
syndrome (PCOS) is a common disorder for women of child‐bearing age and is associated …

[HTML][HTML] Genetic determinants of polycystic ovary syndrome: progress and future directions

MR Jones, MO Goodarzi - Fertility and sterility, 2016 - Elsevier
The field of the genetics of polycystic ovary syndrome (PCOS) has relatively recently moved
into the era of genome-wide association studies. This has led to the discovery of 16 robust …

Genetics of polycystic ovary syndrome: searching for the way out of the labyrinth

E Diamanti-Kandarakis, C Piperi - Human Reproduction Update, 2005 - academic.oup.com
Polycystic ovary syndrome (PCOS) is a complex and heterogeneous disorder presenting a
challenge for clinical investigators. It is the most common endocrine disorder of women in …

Genetics of polycystic ovary syndrome

K Mykhalchenko, D Lizneva, T Trofimova… - Expert review of …, 2017 - Taylor & Francis
Introduction: Polycystic ovary syndrome (PCOS) is a hormonal and metabolic disorder
affecting 5 to 20% of reproductive-aged women worldwide that results in androgen excess …