Oxidative stress, mitochondrial damage and neurodegenerative diseases
C Guo, L Sun, X Chen, D Zhang - Neural regeneration research, 2013 - journals.lww.com
Oxidative stress and mitochondrial damage have been implicated in the pathogenesis of
several neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease …
several neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease …
Mitochondria as a target of environmental toxicants
Enormous strides have recently been made in our understanding of the biology and
pathobiology of mitochondria. Many diseases have been identified as caused by …
pathobiology of mitochondria. Many diseases have been identified as caused by …
Mitochondrial DNA as a marker of molecular diversity: a reappraisal
Over the last three decades, mitochondrial DNA has been the most popular marker of
molecular diversity, for a combination of technical ease‐of‐use considerations, and …
molecular diversity, for a combination of technical ease‐of‐use considerations, and …
[图书][B] Bioenergetics
DG Nicholls - 2013 - books.google.com
Extensively revised, the fourth edition of this highly successful book takes into account the
many newly determined protein structures that provide molecular insight into chemiosmotic …
many newly determined protein structures that provide molecular insight into chemiosmotic …
Mitochondrial function in the human oocyte and embryo and their role in developmental competence
J Van Blerkom - Mitochondrion, 2011 - Elsevier
The role of mitochondria as a nexus of developmental regulation in mammalian oogenesis
and early embryogenesis is emerging from basic research in model species and from …
and early embryogenesis is emerging from basic research in model species and from …
[HTML][HTML] Selective elimination of mitochondrial mutations in the germline by genome editing
Mitochondrial diseases include a group of maternally inherited genetic disorders caused by
mutations in mtDNA. In most of these patients, mutated mtDNA coexists with wild-type …
mutations in mtDNA. In most of these patients, mutated mtDNA coexists with wild-type …
Premature ovarian insufficiency: new perspectives on genetic cause and phenotypic spectrum
Premature ovarian insufficiency (POI) is one form of female infertility, defined by loss of
ovarian activity before the age of 40 and characterized by amenorrhea (primary or …
ovarian activity before the age of 40 and characterized by amenorrhea (primary or …
The role of mitochondrial DNA copy number in mammalian fertility
Mammalian mitochondrial DNA (mtDNA) is a small, maternally inherited genome that codes
for 13 essential proteins in the respiratory chain. Mature oocytes contain more than 150 000 …
for 13 essential proteins in the respiratory chain. Mature oocytes contain more than 150 000 …
Pathogenic mitochondrial DNA mutations are common in the general population
Mitochondrial DNA (mtDNA) mutations are a major cause of genetic disease, but their
prevalence in the general population is not known. We determined the frequency of ten …
prevalence in the general population is not known. We determined the frequency of ten …
Mitochondria, energetics, epigenetics, and cellular responses to stress
DT Shaughnessy, K McAllister, L Worth… - Environmental …, 2014 - ehp.niehs.nih.gov
Background: Cells respond to environmental stressors through several key pathways,
including response to reactive oxygen species (ROS), nutrient and ATP sensing, DNA …
including response to reactive oxygen species (ROS), nutrient and ATP sensing, DNA …