Therapy resistance: opportunities created by adaptive responses to targeted therapies in cancer

M Labrie, JS Brugge, GB Mills… - Nature reviews Cancer, 2022 - nature.com
Normal cells explore multiple states to survive stresses encountered during development
and self-renewal as well as environmental stresses such as starvation, DNA damage, toxins …

Natural antioxidant evaluation: A review of detection methods

JS Mendonça, RCA Guimarães, VA Zorgetto-Pinheiro… - Molecules, 2022 - mdpi.com
Antioxidants have drawn the attention of the scientific community due to being related to the
prevention of various degenerative diseases. The antioxidant capacity has been extensively …

The interplay of oncogenic signaling, oxidative stress and ferroptosis in cancer

W Zeng, X Long, PS Liu, X Xie - International Journal of Cancer, 2023 - Wiley Online Library
Oncogene‐induced hyper‐proliferation in cancer cells is accompanied by the onset of
different stresses, including DNA‐replication stress, metabolic stress and oxidative stress …

Pd nanoparticles stabilized by bitter gourd polysaccharide with peroxidase properties for H2O2 detection

R Li, Y Zhao, T Zhang, Z Ju, X Ji, Y Cui, L Wang… - International Journal of …, 2023 - Elsevier
The development of nanozymes using noble metal nanoparticles to replace natural
peroxidase in bio-related detection has been gain great interest. Noble metal nanoparticles …

Oxidative stress and reproductive function: The impact of oxidative stress on reproduction: A focus on gametogenesis and fertilization

RJ Aitken, EG Bromfield, Z Gibb - Reproduction, 2022 - rep.bioscientifica.com
In brief Many aspects of the reproductive process are impacted by oxidative stress. This
article summarizes the chemical nature of reactive oxygen species and their role in both the …

Signaling pathways of oxidative stress response: the potential therapeutic targets in gastric cancer

Y Liu, Y Shi, R Han, C Liu, X Qin, P Li, R Gu - Frontiers in immunology, 2023 - frontiersin.org
Gastric cancer is one of the top causes of cancer-related death globally. Although novel
treatment strategies have been developed, attempts to eradicate gastric cancer have been …

Multifunctional nanoparticle-mediated combining therapy for human diseases

X Li, X Peng, M Zoulikha, GF Boafo, KT Magar… - … and Targeted Therapy, 2024 - nature.com
Combining existing drug therapy is essential in developing new therapeutic agents in
disease prevention and treatment. In preclinical investigations, combined effect of certain …

The role of exosomes in human carcinogenesis and cancer therapy—Recent findings from molecular and clinical research

K Stefańska, M Józkowiak, A Angelova Volponi… - Cells, 2023 - mdpi.com
Exosomes are biological nanoscale spherical lipid bilayer vesicles, 40–160 nm in diameter,
produced by most mammalian cells in both physiological and pathological conditions …

Arsenic, oxidative stress and reproductive system

F Zargari, MS Rahaman, R KazemPour… - Journal of …, 2022 - mdpi.com
Infertility is a severe medical problem and is considered a serious global public health issue
affecting a large proportion of humanity. Oxidative stress is one of the most crucial factors …

Mitochondrial fission as a therapeutic target for metabolic diseases: insights into antioxidant strategies

T Yu, L Wang, L Zhang, PA Deuster - Antioxidants, 2023 - mdpi.com
Mitochondrial fission is a crucial process in maintaining metabolic homeostasis in normal
physiology and under conditions of stress. Its dysregulation has been associated with …