[HTML][HTML] γδ T cells: origin and fate, subsets, diseases and immunotherapy
Y Hu, Q Hu, Y Li, L Lu, Z Xiang, Z Yin… - … and Targeted Therapy, 2023 - nature.com
The intricacy of diseases, shaped by intrinsic processes like immune system exhaustion and
hyperactivation, highlights the potential of immune renormalization as a promising strategy …
hyperactivation, highlights the potential of immune renormalization as a promising strategy …
Neuroinflammation: An astrocyte perspective
Astrocytes are abundant glial cells in the central nervous system (CNS) that play active roles
in health and disease. Recent technologies have uncovered the functional heterogeneity of …
in health and disease. Recent technologies have uncovered the functional heterogeneity of …
[HTML][HTML] Role of CD93 in Health and Disease
CD93 (also known as complement protein 1 q subcomponent receptor C1qR1 or C1qRp), is
a transmembrane glycoprotein encoded by a gene located on 20p11. 21 and composed of …
a transmembrane glycoprotein encoded by a gene located on 20p11. 21 and composed of …
[HTML][HTML] NF-κB in biology and targeted therapy: new insights and translational implications
Q Guo, Y Jin, X Chen, X Ye, X Shen, M Lin… - … and Targeted Therapy, 2024 - nature.com
NF-κB signaling has been discovered for nearly 40 years. Initially, NF-κB signaling was
identified as a pivotal pathway in mediating inflammatory responses. However, with …
identified as a pivotal pathway in mediating inflammatory responses. However, with …
[HTML][HTML] The gut microbiota-induced kynurenic acid recruits GPR35-positive macrophages to promote experimental encephalitis
The intricate interplay between gut microbes and the onset of experimental autoimmune
encephalomyelitis (EAE) remains poorly understood. Here, we uncover remarkable …
encephalomyelitis (EAE) remains poorly understood. Here, we uncover remarkable …
[HTML][HTML] Review of the therapeutic potential of Forsythiae Fructus on the central nervous system: active ingredients and mechanisms of action
L Zhang, F Lang, J Feng, J Wang - Journal of Ethnopharmacology, 2023 - Elsevier
Abstract Ethnopharmacological relevance Traditional Chinese medicine has gained
significant attention in recent years owing to its multi-component, multi-target, and multi …
significant attention in recent years owing to its multi-component, multi-target, and multi …
[HTML][HTML] Mechanosensitive Piezo1 channel in physiology and pathophysiology of the central nervous system
B Zong, F Yu, X Zhang, Y Pang, W Zhao, P Sun… - Ageing Research …, 2023 - Elsevier
Since the discovery of the mechanosensitive Piezo1 channel in 2010, there has been a
significant amount of research conducted to explore its regulatory role in the physiology and …
significant amount of research conducted to explore its regulatory role in the physiology and …
[HTML][HTML] Bidirectional crosstalk between the peripheral nervous system and lymphoid tissues/organs
The central nervous system (CNS) influences the immune system generally by regulating
the systemic concentration of humoral substances (eg, cortisol and epinephrine), whereas …
the systemic concentration of humoral substances (eg, cortisol and epinephrine), whereas …
[HTML][HTML] The value of Interferon β in multiple sclerosis and novel opportunities for its anti-viral activity: a narrative literature review
G Bellucci, A Albanese, C Rizzi, V Rinaldi… - Frontiers in …, 2023 - frontiersin.org
Interferon-beta (IFN-β) for Multiple Sclerosis (MS) is turning 30. The COVID-19 pandemic
rejuvenated the interest in interferon biology in health and disease, opening translational …
rejuvenated the interest in interferon biology in health and disease, opening translational …
[HTML][HTML] Personalized use of disease-modifying therapies in multiple sclerosis
CY Lee, KH Chan - Pharmaceutics, 2024 - mdpi.com
Multiple sclerosis is an important neurological disease affecting millions of young patients
globally. It is encouraging that more than ten disease-modifying drugs became available for …
globally. It is encouraging that more than ten disease-modifying drugs became available for …