Introduction Focal therapy (FT) is a promising alternative with curative intent for Low-to
Intermediate-risk localized Prostate Cancer (PCa), claiming better functional outcomes and …

Purpose: Men with localized prostate cancer currently face a number of treatment options
that treat the entire prostate. These can cause significant sexual and urinary side effects …

Purpose: The biology of prostate cancer may be influenced by the index lesion. The
definition of index lesion volume is important for appropriate decision making, especially for …

Background: Key challenges of biopsy-based determination of prostate cancer
aggressiveness include tumour heterogeneity, biopsy-sampling error, and variations in …

Purpose Earlier studies evaluating the effect on quality of life (QoL) of localized prostate
cancer interventions included patients receiving adjuvant hormone therapy, which could …

Purpose To determine the demographic, clinical, decision-making, and quality-of-life factors
that are associated with treatment decision regret among long-term survivors of localized …

BACKGROUND For people with localised prostate cancer, active treatments are effective but
have significant side effects. Minimally invasive treatments that destroy (or ablate) either the …

Background Patients' preferences and expectations should be taken into account in
treatment decision making in the last phase of life. Shared decision making (SDM) is …

Evidence-based practice (EBP) is a major shaping influence in clinical social work practice,
in relation to economic policies, and in professional education. The definition of EBP …

Many newly diagnosed prostate cancers present as low Gleason score tumors that require
no treatment intervention. Distinguishing the many indolent tumors from the minority of lethal …