Thyroid cancer is one of the few malignancies that are increasing in incidence. Recent
advances have improved our understanding of its pathogenesis; these include the …

Squamous cell carcinoma of the oral tongue (SCCOT) is one of the most prevalent tumors of
the head and neck region. Despite advances in treatment, the survival of patients with …

The major cause of cancer mortality is the metastatic spread of tumor cells that can occur via
multiple routes, including the lymphatic vasculature. Recent research has indicated that …

Traditionally, tumor-associated lymphatic vessels have been regarded as passive by-
standers, serving simply as a drainage system for interstitial fluid generated within the tumor …

The pace of research into the lymphatic system continues to accelerate with the availability
of new molecular markers. One such marker, LYVE‐1, the lymphatic receptor for the …

The type of tumor‐infiltrating macrophages may be decisive in tumor immunity,
lymphangiogenesis and in the clinical outcome of cancer. Here, we elucidated the …

The lymphatic system is the primary pathway of metastasis for most human cancers. Recent
research efforts in studying lymphangiogenesis have suggested the existence of a …

The poor prognosis for patients with advanced malignancy relates partly to the inability to
reverse cancer metastasis. In this study we have investigated an integrated immunotherapy …

Recent studies involving animal models of cancer and clinicopathological analyses of
human tumours suggest that the growth of lymphatic vessels (lymphangiogenesis) in or …

Purpose: The clinical significance of intratumoral or peritumoral lymph vessel density is not
known. LYVE-1, a lymphatic endothelium-specific hyaluronan receptor, is a novel lymphatic …