ABSTRACT CD1d molecules are lipid antigen-presenting molecules. They are involved in
presenting these antigens to a unique subpopulation of T cells called natural killer T (NKT) …

To assess the effects of constitutive hepatitis C virus (HCV) gene expression on liver,
transgenic mice carrying the entire HCV open reading frame inserted in the α 1 antitrypsin …

T cells are involved in the pathogenesis of important liver diseases including both
autoimmune liver diseases and viral hepatitis. In addition to playing a crucial role in the …

The hepatitis C virus (HCV) is a major cause of chronic liver disease globally. A chronic
infection can result in liver fibrosis, liver cirrhosis, hepatocellular carcinoma and liver failure …

[Frontiers in Bioscience 7, d1662-1675, July 1, 2002] 1662 MOLECULAR PATHOGENESIS OF T
LYMPHOCYTE-INDUCED LIVER INJURY IN ALCOHO Page 1 [Frontiers in Bioscience 7 …

ABSTRACT NKT cells expressing invariant T-cell receptors are an abundant cell population
in the mouse liver, and much evidence has been accumulating which shows that they play …

Intrahepatic lymphocytes are believed to be involved in the immunopathogenesis of
hepatitis C virus (HCV) infection and the evolution of HCV-induced hepatitis. In the present …

Background Although most Caucasian patients with hereditary haemochromatosis (HH)
show the same mutation in the HFE gene, the phenotypic expression of the disease varies …

Although the liver has been the focus of intensive investigation in many different fields of
study, this largest visceral organ of the body has received only scant attention from …

Background Little is known at the molecular level concerning the differences and/or
similarities between alcohol and hepatitis C virus induced liver disease. Global …