[HTML][HTML] Combined oral contraceptives and venous thromboembolism: review and perspective to mitigate the risk

L Morimont, H Haguet, JM Dogné, U Gaspard… - Frontiers in …, 2021 - frontiersin.org
Many factors must be considered and discussed with women when initiating a contraceptive
method and the risk of venous thromboembolism (VTE) is one of them. In this review, we …

Ethinyl estradiol and 17β-estradiol in combined oral contraceptives: pharmacokinetics, pharmacodynamics and risk assessment

FZ Stanczyk, DF Archer, BR Bhavnani - Contraception, 2013 - Elsevier
The need to seek improved combined oral contraceptive (COC) efficacy, with fewer health
risks and better acceptability, has been ongoing since the introduction of COCs more than …

Hormonal contraceptives: pharmacology tailored to women's health

V De Leo, MC Musacchio, V Cappelli… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND In recent years, several new oral contraceptives have become available. In
some ways, they represent an evolution in terms of individualization and compliance on the …

The pharmacology of dienogest

X Ruan, H Seeger, AO Mueck - Maturitas, 2012 - Elsevier
Dienogest (DNG) is a 19-nortestosterone derivative (a C-19 progestogen) with a
cyanomethyl instead of an ethinyl group at the C-17 position, which may make the …

Metabolic impact of combined hormonal contraceptives containing estradiol

G Grandi, A Napolitano, A Cagnacci - Expert Opinion on Drug …, 2016 - Taylor & Francis
Introduction: Is the replacement of ethinyl-estradiol (EE) with estradiol (E2) in combined
hormonal contraceptives (CHCs) associated with fewer metabolic effects, leading to a further …

The pharmacology of nomegestrol acetate

X Ruan, H Seeger, AO Mueck - Maturitas, 2012 - Elsevier
Nomegestrol acetate (NOMAC) is a 19-norprogesterone derivative with high biological
activity at the progesterone receptor, a weak anti-androgenic effect, but with no binding to …

Prospective measurement of blood pressure and heart rate over 24 h in women using combined oral contraceptives with estradiol

G Grandi, A Xholli, A Napolitano, I Piacenti… - Contraception, 2014 - Elsevier
Abstract Objective Combined oral contraceptives (COCs) containing ethinyl-estradiol are
known to increase blood pressure (BP). We evaluated whether COCs containing estradiol …

[PDF][PDF] Actualización en anticoncepción hormonal

R De la Cuesta Benjumea, C Franco Tejeda… - Inf Ter Sist Nac …, 2011 - sanidad.gob.es
The second more frequently used contraception method in our country is hormonal
contraception. Innovations in composition include the introduction of estradiol valerate as …

[HTML][HTML] Confirmation of the safety of combined oral contraceptives containing oestradiol on the risk of venous thromboembolism

G Grandi, F Facchinetti, J Bitzer - The European Journal of …, 2022 - Taylor & Francis
Hormonal contraceptives, in particular combined oral contraceptives (COCs), were designed
to avoid unintended pregnancy, with the fewest possible side effects and health risks. The …

Modification of body composition and metabolism during oral contraceptives containing non-androgenic progestins in association with estradiol or ethinyl estradiol

G Grandi, I Piacenti, A Volpe… - Gynecological …, 2014 - Taylor & Francis
Aim: To observe the influence on metabolism and body composition of two oral
contraceptives containing non-androgenic progestins in association with estradiol or ethinyl …