Transcriptomic and metabolomic analyses provide insights into the attenuation of neuroinflammation by nervonic acid in MPTP-stimulated PD model mice
X Wang, X Zhu, X Li, Z Li, Y Mao, S Zhang, X Liu… - Food & Function, 2023 - pubs.rsc.org
Nervonic acid is one of the most promising bioactive fatty acids, which is believed to be
beneficial for the recovery of human cognitive disorders. However, the detailed …
beneficial for the recovery of human cognitive disorders. However, the detailed …
Deficient chaperone-mediated autophagy facilitates LPS-induced microglial activation via regulation of the p300/NF-κB/NLRP3 pathway
J Wu, Y Han, H Xu, H Sun, R Wang, H Ren… - Science …, 2023 - science.org
Neuroinflammation is a pathological change that is involved in the progression of
Parkinson's disease. Dysfunction of chaperone-mediated autophagy (CMA) has …
Parkinson's disease. Dysfunction of chaperone-mediated autophagy (CMA) has …
[HTML][HTML] Hypoxia and alpha-Synuclein: inextricable link underlying the pathologic progression of Parkinson's disease
M Guo, X Ji, J Liu - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Parkinson's disease (PD) is the second most common neurodegenerative disease after
Alzheimer's disease, with typical motor symptoms as the main clinical manifestations. At …
Alzheimer's disease, with typical motor symptoms as the main clinical manifestations. At …
Delivering optimal care to people with cognitive impairment in Parkinson's disease: a qualitative study of patient, caregiver, and professional perspectives
JS Pigott, N Davies, E Chesterman, J Read… - Parkinson's …, 2023 - Wiley Online Library
Background. Cognitive impairment is common in Parkinson's disease (PD) and associated
with lower quality of life. Cognitive impairment in PD manifests differently to other dementia …
with lower quality of life. Cognitive impairment in PD manifests differently to other dementia …
[HTML][HTML] Detection of mild cognitive impairment in Parkinson's disease using gradient boosting decision tree models based on multilevel DTI indices
B Chen, M Xu, H Yu, J He, Y Li, D Song… - Journal of Translational …, 2023 - Springer
Background Cognitive dysfunction is the most common non-motor symptom in Parkinson's
disease (PD), and timely detection of a slight cognitive decline is crucial for early treatment …
disease (PD), and timely detection of a slight cognitive decline is crucial for early treatment …
[HTML][HTML] PI3K/AKT signaling activation by roflumilast ameliorates rotenone-induced Parkinson's disease in rats
HA Farid, RH Sayed, MES El-Shamarka… - …, 2023 - Springer
Parkinson's disease (PD) is the second most common progressive age-related
neurodegenerative disorder. Paramount evidence shed light on the role of PI3K/AKT …
neurodegenerative disorder. Paramount evidence shed light on the role of PI3K/AKT …
[HTML][HTML] Baicalein attenuates brain iron accumulation through protecting aconitase 1 from oxidative stress in rotenone-induced parkinson's disease in rats
RZ Liu, S Zhang, W Zhang, XY Zhao, GH Du - Antioxidants, 2022 - mdpi.com
Aconitase 1 (ACO1) links oxidative stress and iron accumulation in Parkinson's disease
(PD). ACO1 loses its aconitase activity and turns into iron regulatory protein 1 (IRP1) upon …
(PD). ACO1 loses its aconitase activity and turns into iron regulatory protein 1 (IRP1) upon …
[HTML][HTML] Monoterpenoid epoxidiol ameliorates the pathological phenotypes of the rotenone-induced Parkinson's disease model by alleviating mitochondrial …
Y Aleksandrova, K Chaprov, A Podturkina… - International journal of …, 2023 - mdpi.com
Parkinson's disease is the second most common neurodegenerative disease. Unfortunately,
there is still no definitive disease-modifying therapy. In our work, the antiparkinsonian …
there is still no definitive disease-modifying therapy. In our work, the antiparkinsonian …
Bioelectronic applications of intrinsically conductive polymers
X Gao, Y Bao, Z Chen, J Lu, T Su… - Advanced Electronic …, 2023 - Wiley Online Library
Since the discovery of conducting polyacetylene in the 1970s, intrinsically conducting
polymers (ICPs) have attracted great attention because of their interesting structure …
polymers (ICPs) have attracted great attention because of their interesting structure …
Engineered Selenium/Human Serum Albumin Nanoparticles for Efficient Targeted Treatment of Parkinson's Disease via Oral Gavage
K Xu, P Huang, Y Wu, T Liu, N Shao, L Zhao, X Hu… - ACS …, 2023 - ACS Publications
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the
degeneration of dopamine (DA) neurons in the midbrain substantia nigra pars compacta …
degeneration of dopamine (DA) neurons in the midbrain substantia nigra pars compacta …