[HTML][HTML] Imaging technology of the lymphatic system

AK Polomska, ST Proulx - Advanced drug delivery reviews, 2021 - Elsevier
The lymphatic system plays critical roles in tissue fluid homeostasis and immunity and has
been implicated in the development of many different pathologies, ranging from …

A real-time in vivo clearance assay for quantification of glymphatic efflux

V Pla, P Bork, A Harnpramukkul, G Olveda… - Cell Reports, 2022 - cell.com
Glymphatic fluid transport eliminates metabolic waste from the brain including amyloid-β, yet
the methodology for studying efflux remains rudimentary. Here, we develop a method to …

Physiological models for in vivo imaging and targeting the lymphatic system: Nanoparticles and extracellular vesicles

D Olmeda, D Cerezo-Wallis, E Castellano-Sanz… - Advanced Drug Delivery …, 2021 - Elsevier
Imaging of the lymphatic vasculature has gained great attention in various fields, not only
because lymphatic vessels act as a key draining system in the body, but also for their …

[HTML][HTML] Minimally invasive method for the point-of-care quantification of lymphatic vessel function

AK Polomska, ST Proulx, D Brambilla, D Fehr… - JCI insight, 2019 - ncbi.nlm.nih.gov
Current clinical methods for the evaluation of lymphatic vessel function, crucial for early
diagnosis and evaluation of treatment response of several pathological conditions, in …

Development and clinical validation of the LymphMonitor technology to quantitatively assess lymphatic function

A Polomska, E Gousopoulos, D Fehr, A Bachmann… - Diagnostics, 2021 - mdpi.com
Current diagnostic methods for evaluating the functionality of the lymphatic vascular system
usually do not provide quantitative data and suffer from many limitations including high …

Opposing roles of endothelial and leukocyte-expressed IL-7Rα in the regulation of psoriasis-like skin inflammation

M Vranova, MC Friess, N Haghayegh Jahromi… - Scientific reports, 2019 - nature.com
The interleukin 7 receptor alpha chain (IL-7Rα) is predominately expressed by lymphocytes,
and activation by its ligand IL-7 supports the development and maintenance of T cells and …

Lymphatic endothelial-cell expressed ACKR3 is dispensable for postnatal lymphangiogenesis and lymphatic drainage function in mice

EC Sigmund, L Baur, P Schineis, J Arasa… - Plos one, 2021 - journals.plos.org
Atypical chemokine receptor ACKR3 (formerly CXCR7) is a scavenging receptor that has
recently been implicated in murine lymphatic development. Specifically, ACKR3-deficiency …

Novel Microfluidic Devices to Model the Interactions Between Lymphatics and Breast Cancer

J Weber - 2023 - openscholarship.wustl.edu
The lymphatic system is responsible for immune circulation and fluid balance in the body. It
accomplishes this by draining interstitial fluid from local tissue and transferring it to lymph …