Circadian rhythms in neurodegenerative disorders

M Nassan, A Videnovic - Nature Reviews Neurology, 2022 - nature.com
Endogenous biological clocks, orchestrated by the suprachiasmatic nucleus, time the
circadian rhythms that synchronize physiological and behavioural functions in humans. The …

Co-evolution of machine learning and digital technologies to improve monitoring of Parkinson's disease motor symptoms

AS Chandrabhatla, IJ Pomeraniec… - NPJ digital …, 2022 - nature.com
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor
impairments such as tremor, bradykinesia, dyskinesia, and gait abnormalities. Current …

Quantification of tremor and bradykinesia in Parkinson's disease using a novel ambulatory monitoring system

A Salarian, H Russmann, C Wider… - IEEE Transactions …, 2007 - ieeexplore.ieee.org
An ambulatory system for quantification of tremor and bradykinesia in patients with
Parkinson's disease (PD) is presented. To record movements of the upper extremities, a …

Sleep disturbance in mental health problems and neurodegenerative disease

KN Anderson, AJ Bradley - Nature and science of sleep, 2013 - Taylor & Francis
Sleep has been described as being of the brain, by the brain, and for the brain. This
fundamental neurobiological behavior is controlled by homeostatic and circadian (24-hour) …

Clinically deployable Kinesia™ technology for automated tremor assessment

JP Giuffrida, DE Riley, BN Maddux… - … : official journal of the …, 2009 - Wiley Online Library
The objective was to design, build, and assess Kinesia™, a wireless system for automated
assessment of Parkinson's disease (PD) tremor. The current standard in evaluating PD is the …

Clinical applications of sensors for human posture and movement analysis: a review

WY Wong, MS Wong, KH Lo - Prosthetics and orthotics …, 2007 - journals.sagepub.com
Measurement of human posture and movement is an important area of research in the
bioengineering and rehabilitation fields. Various attempts have been initiated for different …

Ambulatory monitoring of physical activities in patients with Parkinson's disease

A Salarian, H Russmann… - IEEE Transactions …, 2007 - ieeexplore.ieee.org
A new ambulatory method of monitoring physical activities in Parkinson's disease (PD)
patients is proposed based on a portable data-logger with three body-fixed inertial sensors …

Unobtrusive assessment of activity patterns associated with mild cognitive impairment

TL Hayes, F Abendroth, A Adami, M Pavel… - Alzheimer's & …, 2008 - Elsevier
BACKGROUND: Timely detection of early cognitive impairment is difficult. Measures taken in
the clinic reflect a single snapshot of performance that might be confounded by the …

Behavioral patterns of older adults in assisted living

G Virone, M Alwan, S Dalal, SW Kell… - IEEE transactions on …, 2008 - ieeexplore.ieee.org
In this paper, we examine at-home activity rhythms and present a dozen of behavioral
patterns obtained from an activity monitoring pilot study of 22 residents in an assisted living …

Double blind randomised placebo controlled trial of low dose melatonin for sleep disorders in dementia

M Serfaty, S Kennell‐Webb, J Warner… - … journal of geriatric …, 2002 - Wiley Online Library
Background Disturbance of sleep is common in individuals with dementia where there may
be reversal of the sleep‐wake cycle. People with dementia of the Alzheimer's type have …