Mitochondria are highly dynamic organelles that participate in ATP generation and involve
calcium homeostasis, oxidative stress response, and apoptosis. Dysfunctional or damaged …

Twelve regulated cell death programs have been described. We review in detail the basic
biology of nine including death receptor-mediated apoptosis, death receptor-mediated …

Mitophagy is an evolutionarily conserved cellular process to remove dysfunctional or
superfluous mitochondria, thus fine-tuning mitochondrial number and preserving energy …

The pathogenetic mechanism of contrast-induced acute kidney injury (CI-AKI), which is the
third most common cause of hospital-acquired AKI, has not been elucidated. Previously, we …

Mitochondria are multifunctional subcellular organelles essential for cellular energy
homeostasis and apoptotic cell death. It is, therefore, crucial to maintain mitochondrial …

Autophagy contributes to the maintenance of intracellular homeostasis in most cells of
cardiovascular origin, including cardiomyocytes, endothelial cells, and arterial smooth …

Ischemic disorders, such as myocardial infarction, stroke, and peripheral vascular disease,
are the most common causes of debilitating disease and death in westernized cultures. The …

Coronary microvascular endothelial dysfunction is both a culprit and a victim of diabetes,
and can accelerate diabetes-related microvascular and macrovascular complications by …

Discovery of yeast autophagy-related (ATG) genes and subsequent identification of their
homologs in other organisms have enabled researchers to investigate physiological …

Cisplatin is widely recommended in combination for the treatment of tumors, thus inevitably
increasing the incidence of cisplatin-induced acute kidney injury. Mitophagy is a type of …