Menin inhibitors are novel targeted agents currently in clinical development for the treatment
of genetically defined subsets of acute leukemia. Menin has a tumor suppressor function in …

HOXA9 (Homeobox A9) is a homeotic transcription factor known for more than two decades
to be associated with leukemia. The expression of HOXA9 homeoprotein is associated with …

Pediatric acute myeloid leukemia (AML) is a heterogeneous disease that requires a
multifaceted treatment approach. Although outcomes for low‐risk AML have improved …

Baseline cytogenetic studies at diagnosis remain the single most important determinant of
outcome in patients with acute myeloid leukemia (AML). However, the prognostic role of the …

Acute leukemia is a worldwide disease with an incidence of approximately 4/100 000 per
year; 70% of the cases are acute myeloid leukemia (AML). The salient pathologic feature of …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that is characterized by
the progressive degeneration of both upper motor neurons in the motor cortex and lower …

Two different systems exist for subclassification of acute myeloid leukemia (AML); the World
Health Organization (WHO) Classification and the International Consensus Classification …

Acute myeloid leukemia (AML) is the most common acute leukemia in adults, which is
heterogeneous in terms of morphological, cytogenetic and clinical features. Cytogenetic …

Thyroid carcinoma (THCA) is the most universal endocrine malignancy worldwide.
Unfortunately, a limited number of large-scale analyses have been performed to identify …

Myeloid neoplasm with <10% blasts and t(3;5)(q25.1;q34)/NPM::MLF1: A classification dilemma
Myeloid neoplasm with <10% blasts and t(3;5)(q25.1;q34)/NPM::MLF1: A classification …