Cell therapy practices date back to the 19th century and continue to expand on
investigational and investment grounds. Cell therapy includes stem cell-and non–stem cell …

Regenerative medicine is a new and promising mode of therapy for patients who have
limited or no other options for the treatment of their illness. Due to their pleotropic therapeutic …

Bone tissue engineering approaches have evolved towards addressing the challenges of
tissue mimetic requirements over the years. Different strategies have been combining …

Articular cartilage shows limited self-healing ability owing to its low cellularity and
avascularity. Untreated cartilage defects display an increased propensity to degenerate …

The discrepancies between the findings in preclinical studies, and in vivo testing and clinical
trials have resulted in the gradual decline in drug approval rates over the past decades …

Articular cartilage (AC) has limited capacity for repair. The first attempt to repair cartilage
using tissue engineering was reported in 1977. Since then, cell-based interventions have …

Research in low Earth orbit (LEO) has become more accessible. The 2020
Biomanufacturing in Space Symposium reviewed space-based regenerative medicine …

Soft tissue defects are a common clinical challenge mostly caused by trauma, congenital
anomalies and oncological surgery. Current soft tissue reconstruction options include …

The advancement of tissue engineering for regenerating injured tissues and organs has
progressed significantly in recent years. Various techniques have been used to modify the …

Tendinopathy is a multi-faceted pathology characterized by alterations in tendon
microstructure, cellularity and collagen composition. Challenged by the possibility of …