The most commonly diagnosed breast cancer (BC) subtype is characterized by estrogen
receptor (ER) expression. Treatment of this BC subtype typically involves modalities that …

Cancer is one of the most common causes of death worldwide, and its development is a
result of the complex interaction of genetic factors, environmental cues, and aging. Hormone …

Stress-induced cardiovascular diseases characterized by inflammation are among the
leading causes of morbidity and mortality in postmenopausal women worldwide. Estradiol …

In vitro 3D cancer spheroids (tumoroids) exhibit a drug resistance profile similar to that found
in solid tumors. 3D spheroid culture methods recreate more physiologically relevant …

With the development of social economics and the increase of working pressure, more and
more women are suffering from long-term serious stress and showing symptoms of …

Background/Aim: A wide variety of answers can be found regarding the question of whether
G-protein-coupled estrogen receptor 1 (GPER1) is tumor supportive or tumor suppressive. In …

Cancer‐associated fibroblasts (CAFs) can promote the development and metastasis of
prostate cancer partly by mediating tumor‐associated inflammation. An increasing amount of …

The breakdown of gastrointestinal tract immune homeostasis leads to Crohn's disease (CD).
Mesenchymal stem cells (MSCs) have demonstrated clinical efficacy in treating CD in …

Natural remedies derived from plants have a long history of usage in the treatment of a wide
variety of severe diseases. This study aims to develop a Capparis spinosa (C. spinosa) oil …

Triple-negative breast cancer (TNBC) is a biologically and clinically heterogeneous disease.
The G protein-coupled estrogen receptor (GPER) plays a crucial role in mediating the effect …