Chronic kidney disease

K Kalantar-Zadeh, TH Jafar, D Nitsch, BL Neuen… - The lancet, 2021 - thelancet.com
Chronic kidney disease is a progressive disease with no cure and high morbidity and
mortality that occurs commonly in the general adult population, especially in people with …

[HTML][HTML] Vascular pathologies in chronic kidney disease: pathophysiological mechanisms and novel therapeutic approaches

P Düsing, A Zietzer, PR Goody, MR Hosen… - Journal of molecular …, 2021 - Springer
Cardiovascular disease (CVD) is a major cause of death in patients with chronic kidney
disease (CKD). Both conditions are rising in incidence as well as prevalence, creating poor …

Targeting vascular calcification in chronic kidney disease

AJ Nelson, P Raggi, M Wolf, AM Gold… - Basic to Translational …, 2020 - jacc.org
Cardiovascular (CV) disease remains an important cause of morbidity and mortality for
patients with chronic kidney disease (CKD). Although clustering of traditional risk factors with …

A randomized trial on the effect of phosphate reduction on vascular end points in CKD (IMPROVE-CKD)

ND Toussaint, E Pedagogos, NM Lioufas… - Journal of the …, 2020 - journals.lww.com
Background Hyperphosphatemia is associated with increased fibroblast growth factor 23
(FGF23), arterial calcification, and cardiovascular mortality. Effects of phosphate-lowering …

[HTML][HTML] Empagliflozin attenuates vascular calcification in mice with chronic kidney disease by regulating the NFR2/HO-1 anti-inflammatory pathway through AMPK …

CW Lu, CJ Lee, YJ Hsieh, BG Hsu - International Journal of Molecular …, 2023 - mdpi.com
Vascular calcification (VC) is associated with increased cardiovascular risks in patients with
chronic kidney disease (CKD). Sodium-glucose cotransporter 2 inhibitors, such as …

Phosphate binders in chronic kidney disease: an updated narrative review of recent data

J Floege - Journal of Nephrology, 2020 - Springer
Chronic kidney disease (CKD) is frequently accompanied by hyperphosphatemia. High
serum phosphate usually requires dietary measures, adequate dialysis prescription and/or …

[HTML][HTML] Vascular calcification in chronic kidney disease: an update and perspective

SC Ren, N Mao, S Yi, X Ma, JQ Zou, X Tang… - Aging and …, 2022 - ncbi.nlm.nih.gov
Chronic kidney disease is a devastating condition resulting from irreversible loss of nephron
numbers and function and leading to end-stage renal disease and mineral disorders …

Aortic calcification and arterial stiffness burden in a chronic kidney disease cohort with high cardiovascular risk: baseline characteristics of the impact of phosphate …

NM Lioufas, E Pedagogos, CM Hawley… - American journal of …, 2020 - karger.com
Chronic kidney disease (CKD) is associated with excess cardiovascular morbidity and
mortality compared to the general population. Hyperphosphataemia, associated with …

Intact and C-terminal FGF23 assays—do kidney function, inflammation, and low iron influence relationships with outcomes?

S Sharma, R Katz, AL Bullen… - The Journal of …, 2020 - academic.oup.com
Context Higher fibroblast growth factor-23 (FGF23) concentrations are associated with heart
failure and mortality in diverse populations, but the strengths of associations differ markedly …

Arterial stiffness in chronic kidney disease: a modifiable cardiovascular risk factor?

L Pickup, A Radhakrishnan, JN Townend… - Current opinion in …, 2019 - journals.lww.com
Arterial stiffness in chronic kidney disease: a modifiable c... : Current Opinion in Nephrology
and Hypertension Arterial stiffness in chronic kidney disease: a modifiable cardiovascular risk …