Biomedical applications of mesoporous silica nanoparticles as a drug delivery carrier

H Ahmed, SS Gomte, E Prathyusha… - Journal of Drug Delivery …, 2022 - Elsevier
Mesoporous silica nanoparticles (MSNs) attracted biomedical researchers due to their
unique properties like large surface area, pore-volume, and surface-active groups. These …

Cetyltrimethylammonium bromide in the synthesis of mesoporous silica nanoparticles: general aspects and in vitro toxicity

GC Carvalho, GD Marena, JCF Karnopp, J Jorge… - Advances in Colloid and …, 2022 - Elsevier
Pharmaceutical nanotechnology has become a trend with incalculable advantages in the
applicability of systems in the controlled, safe and effective release of drugs. Among the …

Recent advances in magnetite nanoparticle functionalization for nanomedicine

RC Popescu, E Andronescu, BS Vasile - Nanomaterials, 2019 - mdpi.com
Functionalization of nanomaterials can enhance and modulate their properties and
behaviour, enabling characteristics suitable for medical applications. Magnetite (Fe3O4) …

pH-triggered drug release controlled by poly (styrene sulfonate) growth hollow mesoporous silica nanoparticles

FR Wibowo, OA Saputra, WW Lestari, M Koketsu… - ACS …, 2020 - ACS Publications
In the current report, hollow mesoporous silica (HMS) nanoparticles were successfully
prepared by means of a hard-templating method and further modified with poly (styrene …

Biopharmaceutical and pharmacokinetic aspects of nanocarrier-mediated oral delivery of poorly soluble drugs

D Babadi, S Dadashzadeh, M Osouli… - Journal of Drug Delivery …, 2021 - Elsevier
Many new chemical entities have limited water solubility and therefore show low and/or
variable oral bioavailability. Among the various strategies to overcome this challenge …

Molecular interactions in solid dispersions of poorly water-soluble drugs

TTD Tran, PHL Tran - Pharmaceutics, 2020 - mdpi.com
Physicochemical characterization is a crucial step for the successful development of solid
dispersions, including the determination of drug crystallinity and molecular interactions …

Synthesis of monodispersed hollow mesoporous organosilica and silica nanoparticles with controllable shell thickness using soft and hard templates

Y Fujii, S Zhou, M Shimada, M Kubo - Langmuir, 2023 - ACS Publications
Hollow mesoporous nanoparticles with controllable size (less than 100 nm) are desired as
drug-delivery carriers. Herein, we report the synthesis of monodispersed hollow …

Optimization of mirtazapine loaded into mesoporous silica nanostructures via Box-Behnken design: in-vitro characterization and in-vivo assessment

AA Musallam, MA Mahdy, HM Elnahas, RA Aldeeb - Drug Delivery, 2022 - Taylor & Francis
Employment of mesoporous silica nanostructures (MSNs) in the drug delivery field has
shown a significant potential for improving the oral delivery of active pharmaceutical …

[HTML][HTML] Oral cyclodextrin supramolecular for ulcerative colitis treatment through macrophages targeting/ROS response-based accurate on-demand drug release …

H Xu, L Dai, W Nie, R Luo, X Pu, L Dong, Q Chen, S Qi… - Materials & Design, 2023 - Elsevier
Cyclodextrins (CDs) have been applied widely as an oral micro-nano drug delivery material
for the treatment of ulcerative colitis (UC) because of their stability around the stomach …

[HTML][HTML] High storage capacity of curcumin loaded onto hollow mesoporous silica nanoparticles prepared via improved hard-templating method optimized by Taguchi …

OA Saputra, FR Wibowo, WW Lestari - Engineering Science and …, 2022 - Elsevier
The ability of drug carriers, such as silica nanoparticles, to store high-concentrated bioactive
compounds like curcumin within their mesoporous structure is technologically and …