Interferon and interferon-stimulated genes in HBV treatment
Q Li, B Sun, Y Zhuo, Z Jiang, R Li, C Lin, Y Jin… - Frontiers in …, 2022 - frontiersin.org
Human hepatitis B virus (HBV) is a small enveloped DNA virus with a complex life cycle. It is
the causative agent of acute and chronic hepatitis. HBV can resist immune system …
the causative agent of acute and chronic hepatitis. HBV can resist immune system …
Toll-like receptor-mediated innate immunity orchestrates adaptive immune responses in HBV infection
Y Du, J Wu, J Liu, X Zheng, D Yang, M Lu - Frontiers in Immunology, 2022 - frontiersin.org
Chronic hepatitis B virus (HBV) infection remains to be a substantial global burden,
especially for end-stage liver diseases. It is well accepted that HBV-specific T and B cells are …
especially for end-stage liver diseases. It is well accepted that HBV-specific T and B cells are …
Cholesterol accumulation on dendritic cells reverses chronic hepatitis B virus infection-induced dysfunction
H Zhao, Y Yu, Y Wang, L Zhao, A Yang, Y Hu… - Cellular & Molecular …, 2022 - nature.com
Chronic hepatitis B (CHB) infection remains a serious public health problem worldwide;
however, the relationship between cholesterol levels and CHB remains unclear. We isolated …
however, the relationship between cholesterol levels and CHB remains unclear. We isolated …
[HTML][HTML] The hepatic GABAergic system promotes liver macrophage M2 polarization and mediates HBV replication in mice
Z Bao, X Chen, Y Li, W Jiang, D Pan, L Ma, Y Wu… - Antiviral Research, 2023 - Elsevier
Macrophages display functional phenotypic plasticity. Hepatitis B virus (HBV) infection
induces polarizations of liver macrophages either to M1-like pro-inflammatory phenotype or …
induces polarizations of liver macrophages either to M1-like pro-inflammatory phenotype or …
Hepatitis B and Hepatitis D Viruses: A Comprehensive update with an immunological focus
DG Sausen, O Shechter, W Bietsch, Z Shi… - International Journal of …, 2022 - mdpi.com
Hepatitis B virus (HBV) and hepatitis delta virus (HDV) are highly prevalent viruses
estimated to infect approximately 300 million people and 12–72 million people worldwide …
estimated to infect approximately 300 million people and 12–72 million people worldwide …
Epigenetic addition of m5C to HBV transcripts promotes viral replication and evasion of innate antiviral responses
S Ding, H Liu, L Liu, L Ma, Z Chen, M Zhu, L Liu… - Cell Death & …, 2024 - nature.com
Eukaryotic five-methylcytosine (m5C) is an important regulator of viral RNA splicing, stability,
and translation. However, its role in HBV replication remains largely unknown. In this study …
and translation. However, its role in HBV replication remains largely unknown. In this study …
Intracellular antibody targeting HBx suppresses invasion and metastasis in hepatitis B virus‐related hepatocarcinogenesis via protein phosphatase 2A‐B56γ …
L Che, ZB Du, WH Wang, JS Wu, T Han… - Cell …, 2022 - Wiley Online Library
Abstract Objectives Hepatitis B virus X (HBx) is closely associated with HBV‐related
hepatocarcinogenesis via the inactivation of tumour suppressors. Protein phosphatase 2A …
hepatocarcinogenesis via the inactivation of tumour suppressors. Protein phosphatase 2A …
Adenosine triphosphate in serum as a promising biomarker for differential diagnosis of hepatitis B disease progression
C Lin, Y Huang, L Luo, F Fang, J Zhang, Z Xun… - Frontiers in …, 2022 - frontiersin.org
The need to be diagnosed with liver biopsy makes the clinical progression of chronic HBV
infection diagnosis a challenge. Existing HBV serum biochemical assays are used …
infection diagnosis a challenge. Existing HBV serum biochemical assays are used …
[HTML][HTML] 二乙基亚硝胺诱导肝细胞癌模型鼠肠道微生态研究
Z Wenbin, Y ZHENG, J SHANG… - Journal of Zhejiang …, 2022 - ncbi.nlm.nih.gov
目的: 探索肝细胞癌模型鼠肠道微生态特征. 方法: 将2 周龄C57BL/6 雄鼠分为正常对照组和肝癌
模型组. 肝癌模型组在出生后2 周给予单次腹腔注射二乙基亚硝胺(DEN), 其中存活小鼠自4 …
模型组. 肝癌模型组在出生后2 周给予单次腹腔注射二乙基亚硝胺(DEN), 其中存活小鼠自4 …
[HTML][HTML] Antibiotic-induced gut bacteria depletion has no effect on HBV replication in HBV immune tolerance mouse model
Y Bu, K Zhao, Z Xu, Y Zheng, R Hua, C Wu, C Zhu… - Virologica Sinica, 2023 - Elsevier
Commensal microbiota is closely related to Hepatitis B virus (HBV) infection. Gut bacteria
maturation accelerates HBV immune clearance in hydrodynamic injection (HDI) HBV mouse …
maturation accelerates HBV immune clearance in hydrodynamic injection (HDI) HBV mouse …