Revealing protein–lncRNA interaction

F Ferre, A Colantoni… - Briefings in …, 2016 - academic.oup.com
Long non-coding RNAs (lncRNAs) are associated to a plethora of cellular functions, most of
which require the interaction with one or more RNA-binding proteins (RBPs); similarly, RBPs …

How cells get the message: dynamic assembly and function of mRNA–protein complexes

M Müller-McNicoll, KM Neugebauer - Nature Reviews Genetics, 2013 - nature.com
Abstract mRNA is packaged into ribonucleoprotein particles called mRNPs. A multitude of
RNA-binding proteins as well as a host of associated proteins participate in the fate of …

PolyASite 2.0: a consolidated atlas of polyadenylation sites from 3′ end sequencing

CJ Herrmann, R Schmidt, A Kanitz, P Artimo… - Nucleic acids …, 2020 - academic.oup.com
Generated by 3′ end cleavage and polyadenylation at alternative polyadenylation (poly
(A)) sites, alternative terminal exons account for much of the variation between human …

The RNA-binding protein repertoire of embryonic stem cells

SC Kwon, H Yi, K Eichelbaum, S Föhr… - Nature structural & …, 2013 - nature.com
RNA-binding proteins (RBPs) have essential roles in RNA-mediated gene regulation, and
yet annotation of RBPs is limited mainly to those with known RNA-binding domains. To …

Predicting RNA-protein interactions using only sequence information

UK Muppirala, VG Honavar, D Dobbs - BMC bioinformatics, 2011 - Springer
Background RNA-protein interactions (RPIs) play important roles in a wide variety of cellular
processes, ranging from transcriptional and post-transcriptional regulation of gene …

[PDF][PDF] Sex differences in developmental programming models

CE Aiken, SE Ozanne - Reproduction, 2013 - researchgate.net
The theory of developmental programming suggests that diseases such as the metabolic
syndrome may be 'programmed'by exposure to adverse stimuli during early development …

The regulation of mRNA stability in mammalian cells: 2.0

X Wu, G Brewer - Gene, 2012 - Elsevier
Messenger RNA decay is an essential step in gene expression to set mRNA abundance in
the cytoplasm. The binding of proteins and/or noncoding RNAs to specific recognition …

NPI-GNN: predicting ncRNA–protein interactions with deep graph neural networks

ZA Shen, T Luo, YK Zhou, H Yu… - Briefings in …, 2021 - academic.oup.com
Noncoding RNAs (ncRNAs) play crucial roles in many biological processes. Experimental
methods for identifying ncRNA–protein interactions (NPIs) are always costly and time …

RPI-Pred: predicting ncRNA-protein interaction using sequence and structural information

V Suresh, L Liu, D Adjeroh, X Zhou - Nucleic acids research, 2015 - academic.oup.com
RNA-protein complexes are essential in mediating important fundamental cellular
processes, such as transport and localization. In particular, ncRNA-protein interactions play …

RNA binding proteins in intestinal epithelial biology and colorectal cancer

P Chatterji, AK Rustgi - Trends in molecular medicine, 2018 - cell.com
The intestinal epithelium is highly proliferative and consists of crypt invaginations that house
stem cells and villus projections with differentiated cells. There exists a dynamic equilibrium …