Cell plasticity represents the ability of cells to be reprogrammed and to change their fate and
identity, enabling homeostasis restoration and tissue regeneration following damage. Cell …

Lineage plasticity, the ability of cells to transition from one committed developmental
pathway to another, has been proposed as a source of intratumoural heterogeneity and of …

Chronic inflammation promotes the development of several types of solid cancers and might
contribute to prostate carcinogenesis. This hypothesis partly originates in the frequent …

Lineage plasticity, a process whereby cells change their phenotype to take on a different
molecular and/or histologic identity, is a key driver of cancer progression and therapy …

A comprehensive cellular anatomy of normal human prostate is essential for solving the
cellular origins of benign prostatic hyperplasia and prostate cancer. The tools used to …

Prostate cancer is a major cause of cancer morbidity and mortality. Intra-prostatic
inflammation is a risk factor for prostate carcinogenesis, with diet, chemical injury and an …

The relationship between inflammation and cancer has been recognized since the 17th
century, 1 and we now know much about the cells, cytokines and physiological processes …

Glandular epithelia, including the mammary and prostate glands, are composed of basal
cells (BCs) and luminal cells (LCs),. Many glandular epithelia develop from multipotent …

Prostate organogenesis is a complex process that is primarily mediated by the presence of
androgens and subsequent mesenchyme-epithelial interactions. The investigation of …

Simple Summary The cancer cells in solid tumors are embedded in a complex connective
tissue matrix composed of various other cell types, ie, mesenchymal stroma/stem-like cells …