Mass spectrometry-based metabolomics in microbiome investigations
A Bauermeister, H Mannochio-Russo… - Nature Reviews …, 2022 - nature.com
Microbiotas are a malleable part of ecosystems, including the human ecosystem.
Microorganisms affect not only the chemistry of their specific niche, such as the human gut …
Microorganisms affect not only the chemistry of their specific niche, such as the human gut …
Metformin: Update on mechanisms of action and repurposing potential
Currently, metformin is the first-line medication to treat type 2 diabetes mellitus (T2DM) in
most guidelines and is used daily by> 200 million patients. Surprisingly, the mechanisms …
most guidelines and is used daily by> 200 million patients. Surprisingly, the mechanisms …
Unravelling the collateral damage of antibiotics on gut bacteria
Antibiotics are used to fight pathogens but also target commensal bacteria, disturbing the
composition of gut microbiota and causing dysbiosis and disease. Despite this well-known …
composition of gut microbiota and causing dysbiosis and disease. Despite this well-known …
The gut microbiota–brain axis in behaviour and brain disorders
LH Morais, HL Schreiber IV… - Nature Reviews …, 2021 - nature.com
In a striking display of trans-kingdom symbiosis, gut bacteria cooperate with their animal
hosts to regulate the development and function of the immune, metabolic and nervous …
hosts to regulate the development and function of the immune, metabolic and nervous …
Gut microbiota in human metabolic health and disease
Y Fan, O Pedersen - Nature Reviews Microbiology, 2021 - nature.com
Observational findings achieved during the past two decades suggest that the intestinal
microbiota may contribute to the metabolic health of the human host and, when aberrant, to …
microbiota may contribute to the metabolic health of the human host and, when aberrant, to …
Multimodal interactions of drugs, natural compounds and pollutants with the gut microbiota
AE Lindell, M Zimmermann-Kogadeeva… - Nature Reviews …, 2022 - nature.com
The gut microbiota contributes to diverse aspects of host physiology, ranging from
immunomodulation to drug metabolism. Changes in the gut microbiota composition are …
immunomodulation to drug metabolism. Changes in the gut microbiota composition are …
Gut microbiota and its metabolites in depression: from pathogenesis to treatment
L Liu, H Wang, X Chen, Y Zhang, H Zhang, P Xie - EBioMedicine, 2023 - thelancet.com
Major depressive disorder is one of the most disabling mental disorders worldwide.
Increasing preclinical and clinical studies have highlighted that compositional and functional …
Increasing preclinical and clinical studies have highlighted that compositional and functional …
Combinatorial, additive and dose-dependent drug–microbiome associations
SK Forslund, R Chakaroun… - Nature, 2021 - nature.com
During the transition from a healthy state to cardiometabolic disease, patients become
heavily medicated, which leads to an increasingly aberrant gut microbiome and serum …
heavily medicated, which leads to an increasingly aberrant gut microbiome and serum …
[HTML][HTML] Guts imbalance imbalances the brain: a review of gut microbiota association with neurological and psychiatric disorders
In the last ten years, there has been a growing interest regarding the relationship between
gut microbiota, brain, and neurological-associated affections. As multiple preclinical and …
gut microbiota, brain, and neurological-associated affections. As multiple preclinical and …
The gut microbiota (microbiome) in cardiovascular disease and its therapeutic regulation
In the last two decades, considerable interest has been shown in understanding the
development of the gut microbiota and its internal and external effects on the intestine, as …
development of the gut microbiota and its internal and external effects on the intestine, as …