Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review

A Pandey, SJ Shah, J Butler, DL Kellogg Jr… - Journal of the American …, 2021 - jacc.org
Exercise intolerance (EI) is the primary manifestation of chronic heart failure with preserved
ejection fraction (HFpEF), the most common form of heart failure among older individuals …

Frailty and heart failure: State‐of‐the‐art review

KM Talha, A Pandey, M Fudim, J Butler… - Journal of Cachexia …, 2023 - Wiley Online Library
At least half of all patients with heart failure (HF) are affected by frailty, a syndrome that limits
an individual ability to recover from acute stressors. While frailty affects up to 90% of patients …

Physical rehabilitation for older patients hospitalized for heart failure

DW Kitzman, DJ Whellan, P Duncan… - … England Journal of …, 2021 - Mass Medical Soc
Background Older patients who are hospitalized for acute decompensated heart failure have
high rates of physical frailty, poor quality of life, delayed recovery, and frequent …

Prevalence and prognostic impact of the coexistence of multiple frailty domains in elderly patients with heart failure: the FRAGILE‐HF cohort study

Y Matsue, K Kamiya, H Saito, K Saito… - European journal of …, 2020 - Wiley Online Library
Aims To describe the prevalence, overlap, and prognostic implications of physical and social
frailties and cognitive dysfunction in hospitalized elderly patients with heart failure. Methods …

Frailty status modifies the efficacy of exercise training among patients with chronic heart failure and reduced ejection fraction: an analysis from the HF-ACTION trial

A Pandey, MW Segar, S Singh, GR Reeves… - Circulation, 2022 - Am Heart Assoc
Background: Supervised aerobic exercise training (ET) is recommended for stable
outpatients with heart failure (HF) with reduced ejection fraction (HFrEF). Frailty, a syndrome …

Frailty, guideline-directed medical therapy, and outcomes in HFrEF: from the GUIDE-IT trial

MS Khan, MW Segar, MS Usman, S Singh, SJ Greene… - Heart Failure, 2022 - jacc.org
Objectives In this study, we sought to evaluate the association of frailty with the use of
optimal guideline-directed medical therapy (GDMT) and outcomes in heart failure with …

Frailty and effects of a multidomain physical rehabilitation intervention among older patients hospitalized for acute heart failure: a secondary analysis of a randomized …

A Pandey, DW Kitzman, MB Nelson, AM Pastva… - JAMA …, 2023 - jamanetwork.com
Importance Frailty is common among older patients with acute decompensated heart failure
(ADHF) and is associated with worse quality of life (QOL) and a higher risk of clinical events …

[HTML][HTML] The prevalence and the impact of frailty in hepato-biliary pancreatic cancers: a systematic review and meta-analysis

K Komici, M Cappuccio, A Scacchi, R Vaschetti… - Journal of Clinical …, 2022 - mdpi.com
Background: Frailty has been associated with increased mortality among hepatobiliary
pancreatic (HBP) cancer patients. Nevertheless, estimates of frailty prevalence in HBP …

Clinical utility of simple subjective gait speed for the risk stratification of heart failure in a primary prevention setting

K Ueno, H Kaneko, K Kamiya, H Itoh, A Okada… - Scientific Reports, 2022 - nature.com
Little is known regarding the relationship between self-reported gait speed and the
subsequent risk of heart failure (HF) and cardiovascular disease (CVD). We sought to clarify …

Assessing and managing frailty in advanced heart failure: An International Society for Heart and Lung Transplantation consensus statement

QE Denfeld, SR Jha, E Fung, T Jaarsma… - The Journal of Heart and …, 2024 - Elsevier
Frailty is increasingly recognized as a salient condition in patients with heart failure (HF) as
previous studies have determined that frailty is highly prevalent and prognostically …