Mammalian oocytes and early cleavage-stage embryos are critically dependent on their~
100,000 mitochondria to develop from ovulation to compacted morula stage. They rely …

Inflammation is a biologic process that mediates tissue effects including vasodilation,
hyperemia, edema, collagenolysis, and cell proliferation through complex immunologic …

Disclosures: This work was supported by grant K12HD063086 from the National Institutes of
Health (NIH), Bethesda, Maryland. The contents of this work are the responsibility of the …

Obesity is associated with infertility in women through multiple and complex mechanisms.
Briefly, the adipose tissue through the production of many factors, such as leptin, free fatty …

Obesity, diabetes, and related metabolic disorders are major health issues worldwide. As
the epidemic of metabolic disorders continues, the associated medical co-morbidities …

The prevalence of obesity in adults worldwide, and specifically in women of reproductive
age, is concerning given the risks to fertility posed by the increased risk of type 2 diabetes …

Background: Obesity in pregnancy has become one of the most important challenges in
obstetrical care given its prevalence and potential adverse impact on both mother and fetus …

Mobilization of fatty acids from adipose tissue during metabolic stress increases the amount
of free fatty acids in blood and follicular fluid and is associated with impaired female fertility …

This study evaluated the impact of elevated body mass index (BMI) on short-and long-term
outcomes of in-vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) treatments. A …

Obesity is associated with low-grade chronic inflammation, which contributes to cellular
dysfunction promoting metabolic disease. Obesity during pregnancy leads to a …