Utility of polygenic risk scores to aid in the diagnosis of rheumatic diseases
L Santiago-Lamelas, R Dos Santos-Sobrín… - Best Practice & …, 2024 - Elsevier
Rheumatic diseases (RDs) are characterized by autoimmunity and autoinflammation and
are recognized as complex due to the interplay of multiple genetic, environmental, and …
are recognized as complex due to the interplay of multiple genetic, environmental, and …
[HTML][HTML] Rheumatoid arthritis increases the risk of malignant neoplasm of bone and articular cartilage: a two-sample bidirectional mendelian randomization study
M Yang, Y Su, K Xu, J Xie, P Wen, L Liu… - Arthritis Research & …, 2023 - Springer
Objective Prior research has revealed a heightened prevalence of neoplasms in individuals
diagnosed with rheumatoid arthritis (RA). The primary objective of this study is to delve into …
diagnosed with rheumatoid arthritis (RA). The primary objective of this study is to delve into …
High prevalence of diffuse idiopathic skeletal hyperostosis (DISH) among obese young patients–A retrospective observational study
S Brikman, Y Lubani, R Mader, A Bieber - Seminars in Arthritis and …, 2024 - Elsevier
Objective Diffuse idiopathic skeletal hyperostosis (DISH) is characterized by ossification of
ligaments and entheses, and most commonly affects the spinal column. The prevalence of …
ligaments and entheses, and most commonly affects the spinal column. The prevalence of …
[HTML][HTML] Association of visceral adipose tissue with gout: Observational and Mendelian randomization analyses
W Xiao, Q Wang, Y Liu, H Zhang… - Chinese Medical …, 2023 - journals.lww.com
Background: The causal relationship between visceral adipose tissue (VAT) and gout is still
unclear. We aimed to examine the potential association between them using observational …
unclear. We aimed to examine the potential association between them using observational …
[HTML][HTML] Phenome-wide causal associations between osteoarthritis and other complex traits through the latent causal variable analysis
L Mei, Z Zhang, R Chen, Z Li - BMC Musculoskeletal Disorders, 2024 - Springer
Background Individuals with osteoarthritis present with comorbidities, and the potential
causal associations remain incompletely elucidated. The present study undertook a large …
causal associations remain incompletely elucidated. The present study undertook a large …
[HTML][HTML] Causality between Ankylosing Spondylitis and osteoarthritis in European ancestry: a bidirectional Mendelian randomization study
Y Lu, D Lu, H Zhang, H Li, B Yu, Y Zhang… - Frontiers in …, 2024 - frontiersin.org
Objective To explore the bidirectional causal relationship between Ankylosing Spondylitis
(AS) and Osteoarthritis (OA) at the genetic level within the European ancestry. Methods We …
(AS) and Osteoarthritis (OA) at the genetic level within the European ancestry. Methods We …
[HTML][HTML] Association between the advanced lung cancer inflammation index and all-cause and cardiovascular mortality in patients with RA: Insights from NHANES …
X Tian, Z Qu, Y Sun, B Zhang - Heliyon, 2024 - cell.com
Background Rheumatoid arthritis (RA) is associated with significant mortality, which is
primarily due to cardiovascular complications. Despite advancements in RA treatment …
primarily due to cardiovascular complications. Despite advancements in RA treatment …
[HTML][HTML] Exploring the Two-Way Link between Migraines and Venous Thromboembolism: A Bidirectional Two-Sample Mendelian Randomization Study
Y Wang, X Hu, X Wang, L Li, P Lou… - Thrombosis and …, 2024 - thieme-connect.com
Background The objective of this study is to utilize Mendelian randomization to scrutinize the
mutual causality between migraine and venous thromboembolism (VTE) thereby addressing …
mutual causality between migraine and venous thromboembolism (VTE) thereby addressing …
Incidence of collagen-induced arthritis is elevated by a high-fat diet without influencing body weight in mice
J Liang, K Yang, Y Shen, X Peng, H Tan, L Liu… - RMD open, 2024 - rmdopen.bmj.com
Obesity is recognised as a risk factor for triggering rheumatoid arthritis (RA), and it can
worsen joint deformities 1 and diminish the quality of life in patients with RA. 2 The reduction …
worsen joint deformities 1 and diminish the quality of life in patients with RA. 2 The reduction …
The impact of body mass index, smoking, alcohol intake on the risk of rotator cuff disease: A Mendelian randomization study
Z Liu, S Hu, M Nie - Frontiers in Genetics, 2023 - frontiersin.org
Background: It is currently showed that body mass index (BMI), smoking and alcohol intake
impact the progression of rotator cuff disease (RCD), but there are disputes regarding their …
impact the progression of rotator cuff disease (RCD), but there are disputes regarding their …