To achieve a complete understanding of how organisms function, there is a need to study
their fundamental unit, the cell, in its spatial context. In recent years, we have seen fast …

In situ transcriptomic techniques promise a holistic view of tissue organization and cell-cell
interactions. There has been a surge of multiplexed RNA in situ mapping techniques but …

One major challenge in neuroscience is to gain a systematic understanding of the
extraordinary diversity of brain cell types and how they contribute to brain function. Spatially …

Multi-omics allows the systematic understanding of the information flow across different
omics layers, while single omics can mainly reflect one aspect of the biological system. The …

Spatial transcriptomics is a newly emerging field that enables high‐throughput investigation
of the spatial localization of transcripts and related analyses in various applications for …

The recent advent of human pluripotent stem cell (PSC)-derived 3D brain organoids has
opened a window into aspects of human brain development that were not accessible before …

Discovery of the genetic components underpinning fundamental and disease-related
processes is being rapidly accelerated by combining efficient, programmable genetic …

Spatial transcriptomics technologies developed in recent years can provide various
information including tissue heterogeneity, which is fundamental in biological and medical …

In recent years, the explosive growth of spatial technologies has enabled the
characterization of spatial heterogeneity of tissue architectures. Compared to traditional …

Single-cell RNA sequencing (scRNA-seq) has been developed for characterizing the
transcriptome of cells that are rare but of biological significance. With cell barcoding and …