Pharmacogenomics can enhance patient care by enabling treatments tailored to genetic
make-up and lowering risk of serious adverse events. As of June 2019, there are 132 …

BACKGROUND Ultrasonography-detected fetal sonographic abnormalities are identified in
2% to 3% of pregnancies. 1 Genetic diagnosis with amniocentesis or chorionic villus …

Objective The development of genomic approaches to prenatal testing such as whole
genome and exome sequencing offers the potential for a better understanding of prenatal …

Whole-exome sequencing (WES) represents a significant breakthrough in the field of human
genetics. This technology has largely contributed to the identification of new disease …

Since the introduction of genome sequencing in medicine, the factors involved in deciding
how to integrate this technology into population screening programs such as Newborn …

Although the potential advantages of clinical germline genome editing (GGE) over currently
available methods are limited, the implementation of GGE in the clinic has been proposed …

The rapidly declining costs and increasing speeds of whole-genome analysis mean that
genetic testing is undergoing a shift from targeted approaches to broader ones that look at …

Objective Genetic counselors need advanced communication skills, particularly when
discussing tests involving massively parallel sequencing. Increasingly, non-genetic …

Objective The aim of this study was to survey the opinions of expectant parents regarding
prenatal whole‐exome sequencing. Methods The study used a questionnaire that focused …

A variety of health-related genetic testing is currently advertized directly to consumers. This
article provides a timely overview of direct-to-consumer genetic testing (DTC GT) and salient …