The leap of retroviruses and coronaviruses from animal hosts to humans has led to two
ongoing pandemics and tens of millions of deaths worldwide. Retrovirus and coronavirus …

A rapidly evolving understanding of phase separation in the biological and physical
sciences has led to the redefining of virus-engineered replication compartments in many …

Summary Polycomb repressive complex 1 (PRC1) undergoes phase separation to form
Polycomb condensates that are multi-component hubs for silencing Polycomb target genes …

Abstract Chromobox protein homolog 4 (CBX4) is a component of the Polycomb group
(PcG) multiprotein Polycomb repressive complexes 1 (PRC1), which is participated in …

Stem cells with the capacity of self-renewal and differentiation play pivotal roles in normal
tissues and malignant tumors. Whereas stem cells are supposed to be genetically identical …

Nucleoporins (NUPs) are cellular effectors of human immunodeficiency virus-1 (HIV-1)
replication that support nucleocytoplasmic trafficking of viral components. However, these …

The phenomenon of phase separation is quite common in cells, and it is involved in multiple
processes of life activities. However, the current research on the correlation between protein …

Polycomb proteins are a fundamental repressive system that plays crucial developmental
roles by orchestrating cell-type-specific transcription programs that govern cell identity …

Background Intrahepatic cholangiocarcinoma (ICCA) is a heterogeneous group of malignant
tumors characterized by high recurrence rate and poor prognosis. Heterochromatin Protein …

Lymph node (LN) metastasis is the dominant cause of death in bladder cancer (BCa)
patients, but the underlying mechanism remains largely unknown. In recent years …