Background The outcome of patients with locally advanced gastroesophageal
adenocarcinoma (adenocarcinoma of the esophagus, gastroesophageal (GE) junction, and …

Background The prognosis of patients with gastroesophageal adenocarcinoma is poor.
There is conflicting evidence regarding effects of preoperative chemotherapy on survival …

Gastric and oesophageal cancers are among the leading causes of cancer-related death
worldwide. By contrast with the decreasing prevalence of gastric cancer, incidence and …

BACKGROUND & AIMS: The molecular mechanism underlying epithelial metaplasia in
Barrett's esophagus remains unknown. Recognizing that Hedgehog signaling is required for …

Introduction: The use of proton-pump inhibitors (PPI) may be associated with an increased
risk of gastric cancer (GC). Objective: To review and meta-analyse available literature …

Background: The border between the esophagus and stomach gives rise to many
discrepancies in the current literature regarding the etiology, classification and surgical …

There has been a remarkable change in the epidemiology of adenocarcinoma of the
esophagogastric junction (AEG) in the western world over the past decades. Previously rare …

Purpose: Despite aggressive chemotherapy, radiotherapy, surgery, or combination
approaches, the survival rate of patients with esophageal cancer remains poor. Recent …

Positron emission tomography (PET)/computed tomography (CT) has important utility and
limitations in the initial staging of esophageal cancer, evaluation of response to neoadjuvant …

BACKGROUND: Esophageal cancer consists of two major histologic types: esophageal
squamous cell carcinoma (ESCC), predominant globally, and esophageal adenocarcinoma …