Review of predicting protein stability changes upon variations

Y Qiu, T Huang, YD Cai - Proteomics, 2024 - Wiley Online Library
Forecasting alterations in protein stability caused by variations holds immense importance.
Improving the thermal stability of proteins is important for biomedical and industrial …

PLMTHP: An Ensemble Framework for Tumor Homing Peptide Prediction based on Protein Language Model

Y Chen, H Qin, X Cui, T Yang, P Sun… - … on Bioinformatics and …, 2023 - ieeexplore.ieee.org
Tumor homing peptides (THPs) play significant role in recognizing and specifically binding
to tumor cells. Traditional experimental methods can accurately identify THPs but often suffer …

Accurate prediction of antibody deamidations by combining high-throughput automated peptide mapping and protein language model-based deep learning

B Niu, B Lee, L Wang, W Chen, J Johnson - 2024 - chemrxiv.org
Therapeutic antibodies such as monoclonal antibodies (mAbs), bispecific and multispecific
antibodies are pivotal in therapeutic protein development and have transformed disease …