Psoriasis and comorbid diseases: epidemiology

J Takeshita, S Grewal, SM Langan, NN Mehta… - Journal of the American …, 2017 - Elsevier
Psoriasis is a common chronic inflammatory disease of the skin that is increasingly being
recognized as a systemic inflammatory disorder. Psoriatic arthritis is a well-known …

Systemic inflammation and cardiovascular comorbidity in psoriasis patients: causes and consequences

WH Boehncke - Frontiers in immunology, 2018 - frontiersin.org
Psoriasis is a common inflammatory skin disease characterized by the appearance of red
scaly plaques that can affect any part of the body. High prevalence, chronicity, disfiguration …

Psoriasis and comorbid diseases: Implications for management

J Takeshita, S Grewal, SM Langan, NN Mehta… - Journal of the American …, 2017 - Elsevier
As summarized in the first article in this continuing medical education series, the currently
available epidemiologic data suggest that psoriasis may be a risk factor for cardiometabolic …

Psoriasis and cardiovascular disease risk in European and East Asian populations: evidence from meta-analysis and Mendelian randomization analysis

L Zhang, Y Wang, L Qiu, J Wu - BMC medicine, 2022 - Springer
Background Psoriasis has been linked to cardiovascular disease (CVD), including coronary
artery disease (CAD), myocardial infarction (MI), and heart failure (HF). However, available …

Psoriasis, metabolic syndrome and cardiovascular risk factors. A population‐based study

JM Fernández‐Armenteros… - Journal of the …, 2019 - Wiley Online Library
Background Psoriasis is a very prevalent systemic chronic inflammatory disease. Major
cardiovascular events are the main cause of mortality in these patients which suggests an …

The relationship between duration of psoriasis, vascular inflammation, and cardiovascular events

A Egeberg, L Skov, AA Joshi, L Mallbris… - Journal of the American …, 2017 - Elsevier
Background Psoriasis is associated with risk of cardiovascular (CV) disease (CVD) and a
major adverse CV event (MACE). Whether psoriasis duration affects risk of vascular …

The risk of fracture among patients with psoriatic arthritis and psoriasis: a population-based study

A Ogdie, L Harter, D Shin, J Baker… - Annals of the …, 2017 - ard.bmj.com
Objective To determine the risk of fracture and osteoporosis among patients with psoriatic
arthritis (PsA) and psoriasis, compared with the general population and patients with …

[HTML][HTML] New frontiers in psoriatic disease research, part II: comorbidities and targeted therapies

D Yan, A Blauvelt, AK Dey, RS Golpanian… - Journal of Investigative …, 2021 - Elsevier
Although psoriasis and psoriatic arthritis (PsA) have been classically considered to be
diseases of the skin and joints, respectively, emerging evidence suggests that a combination …

Looking beyond the skin: pathophysiology of cardiovascular comorbidity in psoriasis and the protective role of biologics

I Andújar, JV Esplugues, P García-Martínez - Pharmaceuticals, 2022 - mdpi.com
Psoriasis is a chronic systemic inflammatory disease associated with a higher incidence of
cardiovascular disease, especially in patients with moderate to severe psoriasis. It has been …

Hyperlipidaemia and IFNgamma/TNFalpha synergism are associated with cholesterol crystal formation in endothelial cells partly through modulation of lysosomal pH …

Y Baumer, AK Dey, CA Gutierrez-Huerta, NO Khalil… - …, 2020 - thelancet.com
Background Inflammation plays an important role in the development of cardiovascular
disease (CVD). Patients with chronic inflammation diseases have high levels of …