[HTML][HTML] Nuclear magnetic resonance spectroscopy in clinical metabolomics and personalized medicine: current challenges and perspectives

MPM Letertre, P Giraudeau, P De Tullio - Frontiers in Molecular …, 2021 - frontiersin.org
Personalized medicine is probably the most promising area being developed in modern
medicine. This approach attempts to optimize the therapies and the patient care based on …

Quantitative NMR spectroscopy of complex mixtures

P Giraudeau - Chemical Communications, 2023 - pubs.rsc.org
Complex mixtures are ubiquitous in many branches of chemistry, be it a complex
pharmaceutical formulation, a collection of biofluids analysed in a metabolomics workflow …

[HTML][HTML] Metabolomic fingerprinting for the detection of early-stage lung cancer: from the genome to the metabolome

JF Haince, P Joubert, H Bach, R Ahmed Bux… - International Journal of …, 2022 - mdpi.com
The five-year survival rate of lung cancer patients is very low, mainly because most newly
diagnosed patients present with locally advanced or metastatic disease. Therefore, early …

[HTML][HTML] No skin off your back: the sampling and extraction of sebum for metabolomics

C Géhin, J Tokarska, SJ Fowler, PE Barran, DK Trivedi - Metabolomics, 2023 - Springer
Introduction Sebum-based metabolomics (a subset of “sebomics”) is a developing field that
involves the sampling, identification, and quantification of metabolites found in human …

[HTML][HTML] Comparison between 5 extractions methods in either plasma or serum to determine the optimal extraction and matrix combination for human metabolomics

M Lepoittevin, Q Blancart-Remaury, T Kerforne… - Cellular & Molecular …, 2023 - Springer
Background Although metabolomics continues to expand in many domains of research,
methodological issues such as sample type, extraction and analytical protocols have not …

[HTML][HTML] Animal metabolite database: Metabolite concentrations in animal tissues and convenient comparison of quantitative metabolomic data

VV Yanshole, AD Melnikov, LV Yanshole… - Metabolites, 2023 - mdpi.com
The Animal Metabolite Database (AMDB, https://amdb. online) is a freely accessible
database with built-in statistical analysis tools, allowing one to browse and compare …

[HTML][HTML] Inflammatory bowel disease and COVID-19: how microbiomics and metabolomics depict two sides of the same coin

GM Cortes, MA Marcialis, F Bardanzellu… - Frontiers in …, 2022 - frontiersin.org
The integrity of the gastrointestinal tract structure and function is seriously compromised by
two pathological conditions sharing, at least in part, several pathogenetic mechanisms …

[HTML][HTML] The exposome paradigm to predict environmental health in terms of systemic homeostasis and resource balance based on NMR data science

J Kikuchi, S Yamada - RSC advances, 2021 - pubs.rsc.org
The environment, from microbial ecosystems to recycled resources, fluctuates dynamically
due to many physical, chemical and biological factors, the profile of which reflects changes …

[HTML][HTML] Metabolomics for the diagnosis of bladder cancer: A systematic review

HA García-Perdomo, AM Dávila-Raigoza… - Asian Journal of …, 2023 - Elsevier
Objective Metabolomics has been extensively utilized in bladder cancer (BCa) research,
employing mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy to …

[HTML][HTML] Metabolomics of infectious diseases in the era of personalized medicine

M Rahman, HE Schellhorn - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Infectious diseases continue to be a major cause of morbidity and mortality worldwide.
Diseases cause perturbation of the host's immune system provoking a response that …