In the last years, traditional natural products have been the center of attention for the
scientific community and exploration of their therapeutic abilities is proceeding permanently …

The discovery of naturally occurring organohalogen compounds has increased
astronomically in the 55 years since they were first discovered─ from fewer than 50 in 1968 …

From the methanolic extract of the climbing stems and rhizomes of Sinomenium acutum, two
new aporphine analogues, acutumalkaloids I and II, were isolated together with fifteen …

Background: Cancer is one of the top two leading causes of death worldwide.
Ethnobotanical research, it is one of methods, which is able to discover effective anticancer …

L-tryptophan metabolism is involved in the regulation of many important physiological
processes, such as, immune response, inflammation, and neuronal function. Indoleamine 2 …

Abstract Indoleamine 2, 3‐dioxygenase 1 (IDO1) is viewed as an extremely promising target
for cancer immunotherapy. Here, we proposed a two‐layer stacking ensemble model …

Abstract Six new alkaloids (1–6) and six known alkaloids (7–12) were obtained from the
stems of Sinomenium acutum. Among them, compounds 1–3 and 6 were four N-oxide …