Bone metastasis is the main cause of death in patients with prostate cancer (PCa), but there
lacks effective treatment method. Immunotherapy shows new hopes for bone metastatic PCa …

Pyroptosis is a novel regulated cell death (RCD) mode associated with inflammation and
innate immunity. Gasdermin E (GSDME), a crucial component of the gasdermin (GSDM) …

Caspases (cysteinyl aspartate-specific proteinases) are a group of structurally similar
proteases in the cytoplasm that can be involved in cell differentiation, programmed death …

Inducing pyroptosis in cancer cells can result in a strong anti-tumor immune response. Our
preliminary study indicates that pyroptosis can be temporarily strengthened by disrupting …

Immunotherapy has good potential to eradicate tumors in the long term. However, due to the
low immunogenicity of tumor cells, current cancer immunotherapies are not effective. To …

Introduction Oral Squamous Cell Carcinoma (OSCC) poses a significant challenge in
oncology due to the absence of precise diagnostic tools, leading to delays in identifying the …

Background Nanotechnology has emerged as a transformative realm of exploration across
diverse scientific domains. A particular focus lies on metal oxide nanoparticles, which boast …

This research work is based on the synthesis of bis-Schiff base derivatives of the
commercially available ibuprofen drug in outstanding yields through multistep reactions …

Background: This research aims to discover novel derivatives having potential therapeutic
applications in treating conditions related to prolyl oligopeptidase (POP) dysfunction …

The main objective of this study is to evaluate the influence of exosomes derived from
endothelial progenitor cells (EPC-Exo) on neointimal formation induced by balloon injury in …