Background Response burden is often defined as the effort required by the patient to answer
a questionnaire. A factor that has been proposed to affect the response burden is …

Health-related quality of life instruments are expected to be of particular value in routine care
of people with multiple sclerosis (MS), where they may facilitate the detection of disease …

Objective: To assess efficacy, safety, and tolerability of every-other-day interferon beta-1b
treatment in patients with a first clinical event suggestive of multiple sclerosis (MS)(clinically …

Background: Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune
disease characterized by unpredictable attacks of the optic nerves and spinal cord that …

Objective The reliability and validity of generic utility measures have not yet been
summarized in people with multiple sclerosis (MS). It is important to assess the psychometric …

OBJECTIVES: Quality of life (QoL) has presently a firmly established position as an
important endpoint in medical care. Multiple sclerosis (MS) is a chronic neurological disease …

Introduction Systematic collection of patient-reported outcome measures (PROMs) during
ambulatory clinic visits can enhance communication between patient and provider, and …

Common disability scales in multiple sclerosis (MS) are often weighted towards physical
disability. Non-motor symptoms such as depression, fatigue and pain substantially influence …

The aim of this article is to compare the applications of the WHO Disability Assessment
Schedule II (WHODAS II) and WHO Quality of Life-BREF (WHOQOL-BREF) in the …

BACKGROUND: Studies assessing psychosocial consequences of multiple sclerosis (MS)
in the community are scarce; it appears that there are no longitudinal surveys in this area …