The S100B protein: A multifaceted pathogenic factor more than a biomarker
F Michetti, ME Clementi, R Di Liddo, F Valeriani… - International Journal of …, 2023 - mdpi.com
S100B is a calcium-binding protein mainly concentrated in astrocytes in the nervous system.
Its levels in biological fluids are recognized as a reliable biomarker of active neural distress …
Its levels in biological fluids are recognized as a reliable biomarker of active neural distress …
Markers of blood-brain barrier disruption increase early and persistently in COVID-19 patients with neurological manifestations
V Bonetto, L Pasetto, I Lisi, M Carbonara… - Frontiers in …, 2022 - frontiersin.org
Background Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is
associated with disorders affecting the peripheral and the central nervous system. A high …
associated with disorders affecting the peripheral and the central nervous system. A high …
[HTML][HTML] Blood biomarkers for traumatic brain injury: A narrative review of current evidence
Introduction A blood-based biomarker (BBBM) test could help to better stratify patients with
traumatic brain injury (TBI), reduce unnecessary imaging, to detect and treat secondary …
traumatic brain injury (TBI), reduce unnecessary imaging, to detect and treat secondary …
Human in vivo evidence of reduced astrocyte activation and neuroinflammation in patients with treatment‐resistant depression following electroconvulsive therapy
Aim The current study aimed to investigate the neuroinflammatory hypothesis of depression
and the potential anti‐inflammatory effect of electroconvulsive therapy (ECT) in vivo, utilizing …
and the potential anti‐inflammatory effect of electroconvulsive therapy (ECT) in vivo, utilizing …
Blood‐based biomarkers and traumatic brain injury—A clinical perspective
Blood‐based biomarkers are promising tools to complement clinical variables and imaging
findings in the diagnosis, monitoring and outcome prediction of traumatic brain injury (TBI) …
findings in the diagnosis, monitoring and outcome prediction of traumatic brain injury (TBI) …
Cerebrospinal Fluid and Serum Biomarker Insights in Aneurysmal Subarachnoid Haemorrhage: Navigating the Brain–Heart Interrelationship for Improved Patient …
The pathophysiological mechanisms underlying severe cardiac dysfunction after
aneurysmal subarachnoid haemorrhage (aSAH) remain poorly understood. In the present …
aneurysmal subarachnoid haemorrhage (aSAH) remain poorly understood. In the present …
Inflammation biomarkers IL‑6 and IL‑10 may improve the diagnostic and prognostic accuracy of currently authorized traumatic brain injury tools
C Tsitsipanis, M Miliaraki, E Paflioti… - Experimental and …, 2023 - spandidos-publications.com
Traumatic brain injury (TBI) is currently one of the leading causes of mortality and disability
worldwide. At present, no reliable inflammatory or specific molecular neurobiomarker exists …
worldwide. At present, no reliable inflammatory or specific molecular neurobiomarker exists …
Double blast wave primary effect on synaptic, glymphatic, myelin, neuronal and neurovascular markers
D Iacono, EK Murphy, CD Stimpson, F Leonessa… - Brain Sciences, 2023 - mdpi.com
Explosive blasts are associated with neurological consequences as a result of blast waves
impact on the brain. Yet, the neuropathologic and molecular consequences due to blast …
impact on the brain. Yet, the neuropathologic and molecular consequences due to blast …
Short-term biological variation of serum glial fibrillary acidic protein
Objectives Serum glial fibrillary acidic protein (GFAP) is an emerging biomarker for
intracerebral diseases and is approved for clinical use in traumatic brain injury. GFAP is also …
intracerebral diseases and is approved for clinical use in traumatic brain injury. GFAP is also …
Clinical complications after a traumatic brain injury and its relation with brain biomarkers
O Yuguero, M Bernal, J Farré, M Martinez-Alonso… - Scientific Reports, 2023 - nature.com
We aimed to find out which are the most frequent complications for patients who suffer a
traumatic brain injury (TBI) and its relation with brain biomarker levels. We conducted a …
traumatic brain injury (TBI) and its relation with brain biomarker levels. We conducted a …