Insulin resistance and acne: the role of metformin as alternative therapy in men

A Andreadi, S Muscoli, R Tajmir, M Meloni, A Minasi… - Pharmaceuticals, 2022 - mdpi.com
The association between acne and insulin resistance has not been investigated as
thoroughly in males as it has been in women, despite the fact that in adult men, acne …

Candidate Genes and Their Expressions Involved in the Regulation of Milk and Meat Production and Quality in Goats (Capra hircus)

JI Salgado Pardo, JV Delgado Bermejo… - Animals, 2022 - mdpi.com
Simple Summary During the present decade, highly selected caprine farming has increased
in popularity due to the hardiness and adaptability inherent to goats. Recent advances in …

[HTML][HTML] Stearoyl-CoA desaturase 1 (SCD1) facilitates the growth and anti-ferroptosis of gastric cancer cells and predicts poor prognosis of gastric cancer

C Wang, M Shi, J Ji, Q Cai, Q Zhao, J Jiang… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Cancer cells are characterized by metabolic alterations. Thereinto, Stearoyl-CoA
Desaturase 1 (SCD1), an enzymatic node located in the conversion of saturated fatty acids …

[HTML][HTML] SREBP1 siRNA enhance the docetaxel effect based on a bone-cancer dual-targeting biomimetic nanosystem against bone metastatic castration-resistant …

J Chen, Z Wu, W Ding, C Xiao, Y Zhang, S Gao… - Theranostics, 2020 - ncbi.nlm.nih.gov
Until recently, there have been limited options for patients with bone metastatic castration-
resistant prostate cancer (BmCRPC) following the failure of or development of resistance to …

Knockout of stearoyl-CoA desaturase 1 decreased milk fat and unsaturated fatty acid contents of the goat model generated by CRISPR/Cas9

H Tian, H Niu, J Luo, W Yao, X Chen, J Wu… - Journal of Agricultural …, 2022 - ACS Publications
Goat milk contains a rich source of nutrients, especially unsaturated fatty acids. However, the
regulatory mechanism of milk fat and fatty acid synthesis remains unclear. Stearoyl-CoA …

LPIN1 promotes triglycerides synthesis and is transcriptionally regulated by PPARG in buffalo mammary epithelial cells

F Zhou, X Fan, Y Miao - Scientific Reports, 2022 - nature.com
Abstract Studies on 3T3-L1 cells and HepG2 hepatocytes have shown that phosphatidic
acid phosphohydrolase1 (LPIN1) plays a key role in adipogenesis, acting as a co-activator …

CRISPR/Cas9-mediated stearoyl-CoA desaturase 1 (SCD1) deficiency affects fatty acid metabolism in goat mammary epithelial cells

H Tian, J Luo, Z Zhang, J Wu, T Zhang… - Journal of agricultural …, 2018 - ACS Publications
Stearoyl-CoA desaturase 1 (SCD1) is a fatty acid desaturase catalyzing cis-double-bond
formation in the Δ9 position to produce monounsaturated fatty acids essential for the …

[HTML][HTML] Chronic ethanol consumption and HBV induce abnormal lipid metabolism through HBx/SWELL1/arachidonic acid signaling and activate Tregs in HBV-Tg …

Z Liu, J Wang, L Liu, H Yuan, Y Bu, J Feng, Y Liu… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Chronic ethanol consumption as a public health problem worldwide boosts the
development of chronic liver diseases in hepatitis B virus (HBV)-infected patients …

Fatty acid biosynthesis and transcriptional regulation of Stearoyl-CoA Desaturase 1 (SCD1) in buffalo milk

Z Li, S Lu, K Cui, L Shafique, S Rehman, C Luo… - BMC genetics, 2020 - Springer
Background Buffalo milk is considered as a highly nutritious food owing to its higher
contents of fatty acids (FA) and rich nutrient profile. Higher fat contents of buffalo milk make it …

Chronic exposure of bumblebees to neonicotinoid imidacloprid suppresses the entire mevalonate pathway and fatty acid synthesis

T Erban, B Sopko, P Talacko, K Harant, K Kadlikova… - Journal of …, 2019 - Elsevier
Determining the side effects of pesticides on pollinators is an important topic due to the
increasing loss of pollinators. We aimed to determine the effects of chronic sublethal …