Metallo-β-lactamases: structure, function, epidemiology, treatment options, and the development pipeline

SE Boyd, DM Livermore, DC Hooper… - Antimicrobial agents …, 2020 - Am Soc Microbiol
Modern medicine is threatened by the global rise of antibiotic resistance, especially among
Gram-negative bacteria. Metallo-β-lactamase (MBL) enzymes are a particular concern and …

[HTML][HTML] Mobile carbapenemase genes in Pseudomonas aeruginosa

EJ Yoon, SH Jeong - Frontiers in microbiology, 2021 - frontiersin.org
Carbapenem-resistant Pseudomonas aeruginosa is one of the major concerns in clinical
settings impelling a great challenge to antimicrobial therapy for patients with infections …

OXA-48-Like β-Lactamases: global epidemiology, treatment options, and development pipeline

SE Boyd, A Holmes, R Peck… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Modern medicine is threatened by the rising tide of antimicrobial resistance, especially
among Gram-negative bacteria, where resistance to β-lactams is most often mediated by β …

Epidemiology of Carbapenem Resistance Determinants Identified in Meropenem-Nonsusceptible Enterobacterales Collected as Part of a Global Surveillance …

KM Kazmierczak, JA Karlowsky… - Antimicrobial agents …, 2021 - Am Soc Microbiol
To estimate the incidence of carbapenem-resistant Enterobacterales (CRE), a global
collection of 81,781 surveillance isolates of Enterobacterales collected from patients in 39 …

Severe Ebola virus disease with vascular leakage and multiorgan failure: treatment of a patient in intensive care

T Wolf, G Kann, S Becker, C Stephan, HR Brodt… - The Lancet, 2015 - thelancet.com
Background In the current epidemic of Ebola virus disease in western Africa, many aid
workers have become infected. Some of these aid workers have been transferred to …

[HTML][HTML] Multi-drug resistance of blood stream, urinary tract and surgical site nosocomial infections of Acinetobacter baumannii and Pseudomonas aeruginosa …

H Motbainor, F Bereded, W Mulu - BMC infectious diseases, 2020 - Springer
Background Multi-drug resistant (MDR) Acinetobacter baumannii and Pseudomonas
aeruginosa are major causes of nosocomial infections globally. They are the current World …

The incidence and prevalence of hospital-acquired (carbapenem-resistant) Acinetobacter baumannii in Europe, Eastern Mediterranean and Africa: a systematic …

O Ayobami, N Willrich, T Harder, IN Okeke… - Emerging microbes & …, 2019 - Taylor & Francis
Due to therapeutic challenges, hospital-acquired infections (HAIs) caused by Acinetobacter
baumannii (HA-AB), particularly carbapenem-resistant strains (HA-CRAB) pose a serious …

[HTML][HTML] Molecular Epidemiology of Carbapenemases in Enterobacteriales from Humans, Animals, Food and the Environment

G Taggar, M Attiq Rheman, P Boerlin, MS Diarra - Antibiotics, 2020 - mdpi.com
The Enterobacteriales order consists of seven families including Enterobacteriaceae,
Erwiniaceae, Pectobacteriaceae, Yersiniaceae, Hafniaceae, Morganellaceae, and …

Impact of introduction of rapid diagnostic tests for malaria on antibiotic prescribing: analysis of observational and randomised studies in public and private healthcare …

H Hopkins, KJ Bruxvoort, ME Cairns, CIR Chandler… - bmj, 2017 - bmj.com
Objectives To examine the impact of use of rapid diagnostic tests for malaria on prescribing
of antimicrobials, specifically antibiotics, for acute febrile illness in Africa and Asia. Design …

[HTML][HTML] Phenotypic and genotypic detection of carbapenemase-producing Escherichia coli and Klebsiella pneumoniae in Accra, Ghana

FP Dwomoh, FCN Kotey, NTKD Dayie, MM Osei… - PLoS …, 2022 - journals.plos.org
Aim To describe the occurrence of carbapenem resistance among multidrug-resistant (MDR)
Escherichia coli and Klebsiella pneumoniae isolated from clinical specimens in Accra using …