[HTML][HTML] Development of extracellular vesicle therapeutics: Challenges, considerations, and opportunities

B Claridge, J Lozano, QH Poh… - Frontiers in Cell and …, 2021 - frontiersin.org
Extracellular vesicles (EVs) hold great promise as therapeutic modalities due to their
endogenous characteristics, however, further bioengineering refinement is required to …

[HTML][HTML] Effect of microgravity on endothelial cell function, angiogenesis, and vessel remodeling during wound healing

L Morbidelli, S Genah, F Cialdai - Frontiers in bioengineering and …, 2021 - frontiersin.org
Wound healing is a complex phenomenon that involves different cell types with various
functions, ie, keratinocytes, fibroblasts, and endothelial cells, all influenced by the action of …

Umbilical cord mesenchymal stem cell‐derived small extracellular vesicles deliver miR‐21 to promote corneal epithelial wound healing through PTEN/PI3K/Akt …

X Liu, X Li, G Wu, P Qi, Y Zhang, Z Liu, X Li… - Stem cells …, 2022 - Wiley Online Library
Objective. Rapid restoration of corneal epithelium integrity after injury is particularly
important for preserving corneal transparency and vision. Mesenchymal stem cells (MSCs) …

Engineered extracellular vesicles: A novel platform for cancer combination therapy and cancer immunotherapy

M Ahmadi, M Hassanpour, J Rezaie - Life Sciences, 2022 - Elsevier
Extracellular vesicles (EVs), phospholipid membrane-bound vesicles, produced by most
cells, contribute to cell-cell communication. They transfer several proteins, lipids, and nucleic …

[HTML][HTML] Mesenchymal stem cell-derived exosome therapy of microbial diseases: from bench to bed

X Wu, S Jin, C Ding, Y Wang, D He, Y Liu - Frontiers in Microbiology, 2022 - frontiersin.org
Microbial diseases are a global health threat, leading to tremendous casualties and
economic losses. The strategy to treat microbial diseases falls into two broad categories …

Skin cell-derived extracellular vesicles: a promising therapeutic strategy for cutaneous injury

M Wang, P Wu, J Huang, W Liu, H Qian, Y Sun… - Burns & …, 2022 - academic.oup.com
Wound healing refers to the healing process that occurs after the skin and other tissues are
separated or damaged by internal or external forces. It is a complex combination of tissue …

[HTML][HTML] Efficacy and safety of small extracellular vesicle interventions in wound healing and skin regeneration: A systematic review and meta-analysis of animal …

ME Al-Masawa, MA Alshawsh, CY Ng, AMH Ng… - Theranostics, 2022 - ncbi.nlm.nih.gov
Small extracellular vesicles (sEVs) have been proposed as a possible solution to the current
lack of therapeutic interventions for endogenous skin regeneration. We conducted a …

Chitosan hydrogel, as a biological macromolecule-based drug delivery system for exosomes and microvesicles in regenerative medicine: A mini review

L Guo, Y Guan, P Liu, L Gao, Z Wang, S Huang, L Peng… - Cellulose, 2022 - Springer
Extracellular vesicles are membrane-packed entities that are involved in various
physiological and pathological processes. Recently, the role of exosomes and microvesicles …

[HTML][HTML] Menstrual fluid factors mediate endometrial repair

LA Salamonsen - Frontiers in Reproductive Health, 2021 - frontiersin.org
Menstruation is a process whereby the outer functionalis layer of the endometrium is shed
each month in response to falling progesterone and estrogen levels in a non-conception …

Extracellular vesicles derived from HBMSCs improved myocardial infarction through inhibiting zinc finger antisense 1 and activating Akt/Nrf2/HO-1 pathway

H Xiao, D Wu, T Yang, W Fu, L Yang, C Hu, H Wan… - …, 2022 - Taylor & Francis
Myocardial infarction (MI) is believed to be one of the most common cardiovascular
diseases, and it is seriously threatening the health of people in the world. The extracellular …