Evolution of natural product scaffolds as potential proteasome inhibitors in developing cancer therapeutics
Homeostasis between protein synthesis and degradation is a critical biological function
involving a lot of precise and intricate regulatory systems. The ubiquitin-proteasome …
involving a lot of precise and intricate regulatory systems. The ubiquitin-proteasome …
Biosynthetic gene clusters with biotechnological applications in novel Antarctic isolates from Actinomycetota
P Bruna, K Núñez-Montero, MJ Contreras… - Applied Microbiology …, 2024 - Springer
Actinomycetota have been widely described as valuable sources for the acquisition of
secondary metabolites. Most microbial metabolites are produced via metabolic pathways …
secondary metabolites. Most microbial metabolites are produced via metabolic pathways …
Diastereoselective and Enantioselective Synthesis of α-p-Methoxyphenoxy-β-Lactones: Dependence on the Stereoelectronic Properties of the β-Hydroxy-α-p …
JM Witte, J Service, MA Addo, B Semakieh… - The Journal of …, 2022 - ACS Publications
Treatment of β-hydroxy-α-p-methoxyphenoxy carboxylic acids derived from the asymmetric
glycolate aldol addition reaction with p-nitrobenzenesulfonyl chloride yielded divergent …
glycolate aldol addition reaction with p-nitrobenzenesulfonyl chloride yielded divergent …
Taxonogenomics of Culturomica massiliensis gen. nov., sp. nov., and Emergencia timonensis gen. nov., sp. nov. new bacteria isolated from human stool microbiota
A Hamame, R Magdy Wasfy, CI Lo, F Fenollar… - Scientific Reports, 2023 - nature.com
Two new bacterial strains, Marseille-P2698T (CSUR P2698= DSM 103,121) and Marseille-
P2260T (CSUR P2260= DSM 101,844= SN18), were isolated from human stools by the …
P2260T (CSUR P2260= DSM 101,844= SN18), were isolated from human stools by the …
Exploring the Potential of Microbial Biomolecules in Advancing Human Health and Environmental Sustainability
Microbial biomolecules have gained significant attention owing to their remarkable capacity
for promoting advancements in human health and environmental sustainability. This chapter …
for promoting advancements in human health and environmental sustainability. This chapter …
Therapeutic Potential of Microbial Metabolites: New Insights and Perspectives
Microbes release important metabolites that regulate various physiological activities inside
and outside of organisms. The human gastrointestinal tract is a reservoir of microbes that …
and outside of organisms. The human gastrointestinal tract is a reservoir of microbes that …
Subtercola endophyticus sp. nov., a cold-adapted bacterium isolated from Abies koreana
L Jiang, Y Peng, J Seo, D Jeon, MG Jo, JH Lee… - Scientific Reports, 2022 - nature.com
A novel Gram-stain-positive, aerobic bacterial strain, designated AK-R2A1-2 T, was isolated
from the surface-sterilized needle leaves of an Abies koreana tree. Strain AK-R2A1-2 T had …
from the surface-sterilized needle leaves of an Abies koreana tree. Strain AK-R2A1-2 T had …
Four-membered ring systems
J Anaya, RM Sánchez - Progress in Heterocyclic Chemistry, 2023 - Elsevier
The chapter covers work published in the calendar year 2021. The synthesis and reactivity
of four-membered heteroatom-containing cycles are reviewed. New developments in the …
of four-membered heteroatom-containing cycles are reviewed. New developments in the …