Recent advances of multifunctional PLGA nanocarriers in the management of triple-negative breast cancer
Even though chemotherapy stands as a standard option in the therapy of TNBC, problems
associated with it such as anemia, bone marrow suppression, immune suppression, toxic …
associated with it such as anemia, bone marrow suppression, immune suppression, toxic …
Emerging targeted therapeutic strategies for the treatment of triple-negative breast cancer
L Kumari, L Mishra, P Patel, N Sharma… - Journal of Drug …, 2023 - Taylor & Francis
Triple-negative breast cancer (TNBC), a subtype of breast cancer that lacks expression of
oestrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor …
oestrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor …
[HTML][HTML] Mebendazole prevents distant organ metastases in part by decreasing ITGβ4 expression and cancer stemness
Breast cancer is the most diagnosed cancer among women. Approximately 15–20% of all
breast cancers are highly invasive triple-negative breast cancer (TNBC) and lack estrogen …
breast cancers are highly invasive triple-negative breast cancer (TNBC) and lack estrogen …
A phthalocyanine-based photosensitizer for effectively combating triple negative breast cancer with enhanced photodynamic anticancer activity and immune response
K Huang, M Yan, H Zhang, J Xue, J Chen - European Journal of Medicinal …, 2022 - Elsevier
Although photodynamic therapy (PDT) has attracted great interest, the photosensitizers in
clinical had weak inhibition on metastasis and invasion of cancers. Additionally the immune …
clinical had weak inhibition on metastasis and invasion of cancers. Additionally the immune …
[HTML][HTML] HER3 functions as an effective therapeutic target in triple negative breast cancer to potentiate the antitumor activity of gefitinib and paclitaxel
Background Triple negative breast cancer (TNBC) represents a significant clinical
challenge. Chemotherapy remains the mainstay for a large part of TNBC patients, whereas …
challenge. Chemotherapy remains the mainstay for a large part of TNBC patients, whereas …
[HTML][HTML] TGFβ governs the pleiotropic activity of NDRG1 in triple-negative breast cancer progression
A López-Tejada, C Griñán-Lisón… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
In triple-negative breast cancer (TNBC), the pleiotropic NDRG1 (N-Myc downstream
regulated gene 1) promotes progression and worse survival, yet contradictory results were …
regulated gene 1) promotes progression and worse survival, yet contradictory results were …
ERK activation modulates invasiveness and Reactive Oxygen Species (ROS) production in triple negative breast cancer cell lines
A Acosta-Casique, JB Montes-Alvarado, M Barragan… - Cellular …, 2023 - Elsevier
Triple negative breast cancer (TNBC) is the breast cancer subtype with the worst prognosis
and still lacks a targeted therapy. In this study, we found increased ERK phosphorylation in …
and still lacks a targeted therapy. In this study, we found increased ERK phosphorylation in …
Upregulation of p300 in paclitaxel-resistant TNBC: implications for cell proliferation via the PCK1/AMPK axis
PW Zhao, JX Cui, XM Wang - The Pharmacogenomics Journal, 2024 - nature.com
Objective To explore the role of p300 in the context of paclitaxel (PTX) resistance in triple-
negative breast cancer (TNBC) cells, focusing on its interaction with the …
negative breast cancer (TNBC) cells, focusing on its interaction with the …
[HTML][HTML] Signaling pathways and natural compounds in triple-negative breast cancer cell line
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer,
having a poor prognosis and rapid metastases. TNBC is characterized by the absence of …
having a poor prognosis and rapid metastases. TNBC is characterized by the absence of …
Molecular pathways and therapeutic targets linked to triple-negative breast cancer (TNBC)
Cancer is a group of diseases characterized by uncontrolled cellular growth, abnormal
morphology, and altered proliferation. Cancerous cells lose their ability to act as anchors …
morphology, and altered proliferation. Cancerous cells lose their ability to act as anchors …