Non-coding RNAs in disease: from mechanisms to therapeutics
Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
[HTML][HTML] Insights into the role of long non-coding RNAs in DNA methylation mediated transcriptional regulation
DNA methylation is one of the most important epigenetic mechanism that governing
regulation of gene expression, aberrant DNA methylation patterns are strongly associated …
regulation of gene expression, aberrant DNA methylation patterns are strongly associated …
From multi-omics approaches to personalized medicine in myocardial infarction
Myocardial infarction (MI) is a prevalent cardiovascular disease characterized by myocardial
necrosis resulting from coronary artery ischemia and hypoxia, which can lead to severe …
necrosis resulting from coronary artery ischemia and hypoxia, which can lead to severe …
LncRNAs and PTEN/PI3K signaling: A symphony of regulation in cancer biology
WH Almalki - Pathology-Research and Practice, 2023 - Elsevier
Abstract The Emergence of Long Non-coding RNAs (lncRNAs) as Key Regulators in Diverse
Biological Processes: A Paradigm Shift in Understanding Gene Expression and its Impact on …
Biological Processes: A Paradigm Shift in Understanding Gene Expression and its Impact on …
Role of the Notch1 signaling pathway in ischemic heart disease
X Peng, S Wang, H Chen… - … Journal of Molecular …, 2023 - spandidos-publications.com
Ischemic heart disease (IHD) is a prevalent cardiovascular disease characterized by the
formation, progression and rupture of atherosclerotic plaque. The Notch signaling pathway …
formation, progression and rupture of atherosclerotic plaque. The Notch signaling pathway …
Apoptosis and myocardial infarction: role of ncRNAs and exosomal ncRNAs
ncRNAs, particularly miRNAs, lncRNAs and circRNAs, are a group of RNAs which, although
they do not encode proteins (however, recent evidence shows that certain circRNAs are …
they do not encode proteins (however, recent evidence shows that certain circRNAs are …
[HTML][HTML] DNA methylation of HOX genes and its clinical implications in cancer
X Hu, Y Wang, X Zhang, C Li, X Zhang, D Yang… - Experimental and …, 2023 - Elsevier
Homeobox (HOX) genes encode highly conserved transcription factors that play vital roles in
embryonic development. DNA methylation is a pivotal regulatory epigenetic signaling mark …
embryonic development. DNA methylation is a pivotal regulatory epigenetic signaling mark …
[HTML][HTML] Long non-coding RNA LHX1-DT regulates cardiomyocyte differentiation through H2A. Z-mediated LHX1 transcriptional activation
Q Yu, B Cai, Y Zhang, J Xu, D Liu, X Zhang, Z Han… - Iscience, 2023 - Elsevier
Long non-coding RNAs (lncRNAs) play widespread roles in various processes. However,
there is still limited understanding of the precise mechanisms through which they regulate …
there is still limited understanding of the precise mechanisms through which they regulate …
Long term exercise-derived exosomal LncRNA CRNDE mitigates myocardial infarction injury through miR-489-3p/Nrf2 signaling axis
W Chen, Q Ye, Y Dong - Nanomedicine: Nanotechnology, Biology and …, 2024 - Elsevier
Myocardial infarction (MI) is a cardiovascular disease and troubles patients all over the
world. Exosomes produced after long-term exercise training were discovered to mediate …
world. Exosomes produced after long-term exercise training were discovered to mediate …
Dexmedetomidine alleviates Hypoxia/reoxygenation-induced mitochondrial dysfunction in cardiomyocytes via activation of Sirt3/Prdx3 pathway
Q Tan, W Dong, Q Wang, L Gao - DARU Journal of Pharmaceutical …, 2024 - Springer
Background Myocardial ischemia/reperfusion injury (MIRI) seriously threatens the health of
people. The mitochondrial dysfunction in cardiomyocytes can promote the progression of …
people. The mitochondrial dysfunction in cardiomyocytes can promote the progression of …